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A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression
View ORCID ProfileMark J. Wall, Emily Hill, View ORCID ProfileRobert Huckstepp, Kerry Barkan, View ORCID ProfileGiuseppe Deganutti, Michele Leuenberger, View ORCID ProfileBarbara Preti, Ian Winfield, Haifeng Wei, View ORCID ProfileWendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, View ORCID ProfileFei-Yue Zhao, View ORCID ProfileDavid Spanswick, Christopher A. Reynolds, View ORCID ProfileMartin Lochner, View ORCID ProfileGraham Ladds, View ORCID ProfileBruno G. Frenguelli
doi: https://doi.org/10.1101/2020.04.04.023945
Mark J. Wall
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Emily Hill
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Robert Huckstepp
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Kerry Barkan
2Department of Pharmacology University of Cambridge Tennis Court Road Cambridge CB2 1PD, UK
Giuseppe Deganutti
3School of Biological Sciences University of Essex Wivenhoe Park Colchester CO4 3SQ, UK
Michele Leuenberger
4Institute of Biochemistry and Molecular Medicine University of Bern 3012 Bern, Switzerland
Barbara Preti
4Institute of Biochemistry and Molecular Medicine University of Bern 3012 Bern, Switzerland
Ian Winfield
2Department of Pharmacology University of Cambridge Tennis Court Road Cambridge CB2 1PD, UK
Haifeng Wei
5NeuroSolutions Ltd, Coventry, UK.
Wendy Imlach
6Department of Physiology Monash Biomedicine Discovery Institute Monash University Innovation Walk Clayton VIC 3800, Australia
Eve Dean
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Cherise Hume
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Stephanie Hayward
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Jess Oliver
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Fei-Yue Zhao
5NeuroSolutions Ltd, Coventry, UK.
David Spanswick
5NeuroSolutions Ltd, Coventry, UK.
6Department of Physiology Monash Biomedicine Discovery Institute Monash University Innovation Walk Clayton VIC 3800, Australia
7Warwick Medical School University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Christopher A. Reynolds
3School of Biological Sciences University of Essex Wivenhoe Park Colchester CO4 3SQ, UK
Martin Lochner
4Institute of Biochemistry and Molecular Medicine University of Bern 3012 Bern, Switzerland
Graham Ladds
2Department of Pharmacology University of Cambridge Tennis Court Road Cambridge CB2 1PD, UK
Bruno G. Frenguelli
1School of Life Sciences University of Warwick Gibbet Hill Rd Coventry CV4 7AL, UK
Article usage
Posted August 04, 2020.
A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression
Mark J. Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli
bioRxiv 2020.04.04.023945; doi: https://doi.org/10.1101/2020.04.04.023945
A biased adenosine A1R agonist elicits analgesia without cardiorespiratory depression
Mark J. Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli
bioRxiv 2020.04.04.023945; doi: https://doi.org/10.1101/2020.04.04.023945
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