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Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium
Satria P. Sajuthi, Peter DeFord, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel CY Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
doi: https://doi.org/10.1101/2020.04.09.034454
Satria P. Sajuthi
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Peter DeFord
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Nathan D. Jackson
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Michael T. Montgomery
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Jamie L. Everman
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Cydney L. Rios
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Elmar Pruesse
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
James D. Nolin
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Elizabeth G. Plender
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
Michael E. Wechsler
2Department of Medicine, National Jewish Health, Denver, CO, 80206 USA
Angel CY Mak
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Celeste Eng
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Sandra Salazar
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Vivian Medina
4Centro de Neumología Pediátrica, San Juan, Puerto Rico
Eric M. Wohlford
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
5Division of Pediatric Allergy and Immunology, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Scott Huntsman
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Deborah A. Nickerson
6Department of Genome Sciences, University of Washington, Seattle, WA, USA
7Northwest Genomics Center, Seattle, WA, USA
8Brotman Baty Institute, Seattle, WA, USA
Soren Germer
9New York Genome Center, NYC, New York
Michael C. Zody
9New York Genome Center, NYC, New York
Gonçalo Abecasis
10Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA
Hyun Min Kang
10Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA
Kenneth M. Rice
11Department of Biostatistics, University of Washington, Seattle, WA, USA
Rajesh Kumar
12Ann and Robert H. Lurie Children’s Hospital of Chicago, Department of Pediatrics, Northwestern University, Chicago, Ill
Sam Oh
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
Jose Rodriguez-Santana
4Centro de Neumología Pediátrica, San Juan, Puerto Rico
Esteban G. Burchard
3Department of Medicine, Therapeutic Sciences University of California San Francisco, San Francisco, CA
13Department of Bioengineering and Therapeutic Sciences University of California San Francisco, San Francisco, CA
Max A. Seibold
1Center for Genes, Environment, and Health, National Jewish Health, Denver, CO, 80206 USA
14Department of Pediatrics, National Jewish Health, Denver, CO, 80206 USA
15Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado-AMC, Aurora, CO, 80045 USA
Posted April 10, 2020.
Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium
Satria P. Sajuthi, Peter DeFord, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel CY Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
bioRxiv 2020.04.09.034454; doi: https://doi.org/10.1101/2020.04.09.034454
Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium
Satria P. Sajuthi, Peter DeFord, Nathan D. Jackson, Michael T. Montgomery, Jamie L. Everman, Cydney L. Rios, Elmar Pruesse, James D. Nolin, Elizabeth G. Plender, Michael E. Wechsler, Angel CY Mak, Celeste Eng, Sandra Salazar, Vivian Medina, Eric M. Wohlford, Scott Huntsman, Deborah A. Nickerson, Soren Germer, Michael C. Zody, Gonçalo Abecasis, Hyun Min Kang, Kenneth M. Rice, Rajesh Kumar, Sam Oh, Jose Rodriguez-Santana, Esteban G. Burchard, Max A. Seibold
bioRxiv 2020.04.09.034454; doi: https://doi.org/10.1101/2020.04.09.034454
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