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Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of RBD mutant with lower ACE2 binding affinity
View ORCID ProfileYong Jia, Gangxu Shen, Yujuan Zhang, Keng-Shiang Huang, Hsing-Ying Ho, Wei-Shio Hor, Chih-Hui Yang, View ORCID ProfileChengdao Li, Wei-Lung Wang
doi: https://doi.org/10.1101/2020.04.09.034942
Yong Jia
1College of Science, Health, Engineering and Education, Murdoch University, Murdoch, WA, 6150, Australia
Gangxu Shen
2School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan
3National Changhua University of Education, Changhua, Taiwan
Yujuan Zhang
1College of Science, Health, Engineering and Education, Murdoch University, Murdoch, WA, 6150, Australia
Keng-Shiang Huang
2School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan
4College of Medicine, I-Shou University, Kaohsiung, Taiwan
Hsing-Ying Ho
5Guo-Yuan Clinic, Taichung, Taiwan
Wei-Shio Hor
6TOPO Pharmaceutical Co., Ltd, Taichung, Taiwan
Chih-Hui Yang
4College of Medicine, I-Shou University, Kaohsiung, Taiwan
Chengdao Li
1College of Science, Health, Engineering and Education, Murdoch University, Murdoch, WA, 6150, Australia
7Department of Primary Industry and Regional Development, Government of Western Australia, South Perth, WA, 6155, Australia
Wei-Lung Wang
3National Changhua University of Education, Changhua, Taiwan
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Posted April 11, 2020.
Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of RBD mutant with lower ACE2 binding affinity
Yong Jia, Gangxu Shen, Yujuan Zhang, Keng-Shiang Huang, Hsing-Ying Ho, Wei-Shio Hor, Chih-Hui Yang, Chengdao Li, Wei-Lung Wang
bioRxiv 2020.04.09.034942; doi: https://doi.org/10.1101/2020.04.09.034942
Analysis of the mutation dynamics of SARS-CoV-2 reveals the spread history and emergence of RBD mutant with lower ACE2 binding affinity
Yong Jia, Gangxu Shen, Yujuan Zhang, Keng-Shiang Huang, Hsing-Ying Ho, Wei-Shio Hor, Chih-Hui Yang, Chengdao Li, Wei-Lung Wang
bioRxiv 2020.04.09.034942; doi: https://doi.org/10.1101/2020.04.09.034942
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