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Cdk5 and GSK3β inhibit Fast Endophilin-Mediated Endocytosis

Antonio P. A. Ferreira, Alessandra Casamento, Sara Carrillo Roas, James Panambalana, Shaan Subramaniam, Kira Schützenhofer, Els F. Halff, Laura Chan Wah Hak, Kieran McGourty, View ORCID ProfileJosef T. Kittler, Konstantinos Thalassinos, Denis Martinvalet, View ORCID ProfileEmmanuel Boucrot
doi: https://doi.org/10.1101/2020.04.11.036863
Antonio P. A. Ferreira
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
2Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
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Alessandra Casamento
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
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Sara Carrillo Roas
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
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James Panambalana
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
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Shaan Subramaniam
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
8Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK
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Kira Schützenhofer
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
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Els F. Halff
3Department of Neuroscience, Physiology, and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
4Department of Psychosis studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, De Crespigny Park, London SE5 8AB
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Laura Chan Wah Hak
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
5Centre for Neural Circuits and Behaviour, University of Oxford, Mansfield Road, Oxford, OX1 3SR, UK
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Kieran McGourty
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
6Department of Chemical Sciences, Bernal Institute, University of Limerick, IRL
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Josef T. Kittler
3Department of Neuroscience, Physiology, and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
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  • ORCID record for Josef T. Kittler
Konstantinos Thalassinos
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
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Denis Martinvalet
7Department of Biochemistry, University of Padova, 35121 Padova, Italy
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Emmanuel Boucrot
1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
8Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK
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  • ORCID record for Emmanuel Boucrot
  • For correspondence: e.boucrot@ucl.ac.uk
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Article Information

doi 
https://doi.org/10.1101/2020.04.11.036863
History 
  • April 12, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Antonio P. A. Ferreira1,2,*,
  2. Alessandra Casamento1,*,
  3. Sara Carrillo Roas1,
  4. James Panambalana1,
  5. Shaan Subramaniam1,8,
  6. Kira Schützenhofer1,
  7. Els F. Halff3,4,
  8. Laura Chan Wah Hak1,5,
  9. Kieran McGourty1,6,
  10. Josef T. Kittler3,
  11. Konstantinos Thalassinos1,
  12. Denis Martinvalet7 and
  13. Emmanuel Boucrot1,8,$
  1. 1Institute of Structural and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
  2. 2Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
  3. 3Department of Neuroscience, Physiology, and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
  4. 4Department of Psychosis studies, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, De Crespigny Park, London SE5 8AB
  5. 5Centre for Neural Circuits and Behaviour, University of Oxford, Mansfield Road, Oxford, OX1 3SR, UK
  6. 6Department of Chemical Sciences, Bernal Institute, University of Limerick, IRL
  7. 7Department of Biochemistry, University of Padova, 35121 Padova, Italy
  8. 8Institute of Structural and Molecular Biology, Birkbeck College, Malet Street, London WC1E 7HX, UK
  1. ↵$Correspondence: e.boucrot{at}ucl.ac.uk
  1. ↵* contributed equally to this work

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Cdk5 and GSK3β inhibit Fast Endophilin-Mediated Endocytosis
Antonio P. A. Ferreira, Alessandra Casamento, Sara Carrillo Roas, James Panambalana, Shaan Subramaniam, Kira Schützenhofer, Els F. Halff, Laura Chan Wah Hak, Kieran McGourty, Josef T. Kittler, Konstantinos Thalassinos, Denis Martinvalet, Emmanuel Boucrot
bioRxiv 2020.04.11.036863; doi: https://doi.org/10.1101/2020.04.11.036863
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Cdk5 and GSK3β inhibit Fast Endophilin-Mediated Endocytosis
Antonio P. A. Ferreira, Alessandra Casamento, Sara Carrillo Roas, James Panambalana, Shaan Subramaniam, Kira Schützenhofer, Els F. Halff, Laura Chan Wah Hak, Kieran McGourty, Josef T. Kittler, Konstantinos Thalassinos, Denis Martinvalet, Emmanuel Boucrot
bioRxiv 2020.04.11.036863; doi: https://doi.org/10.1101/2020.04.11.036863

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