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Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics

Longlong Si, Haiqing Bai, Melissa Rodas, Wuji Cao, Crystal Yuri Oh, Amanda Jiang, Atiq Nurani, Danni Y. Zhu, Girija Goyal, Sarah E. Gilpin, Rachelle Prantil-Baun, Donald E. Ingber
doi: https://doi.org/10.1101/2020.04.13.039917
Longlong Si
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Haiqing Bai
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Melissa Rodas
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Wuji Cao
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Crystal Yuri Oh
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Amanda Jiang
3Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115
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Atiq Nurani
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Danni Y. Zhu
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Girija Goyal
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Sarah E. Gilpin
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Rachelle Prantil-Baun
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
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Donald E. Ingber
1Wyss Institute for Biologically Inspired Engineering, Boston, MA 02115
2Harvard John A. Paulson School of Engineering and Applied Sciences, Cambridge, MA 02139
3Vascular Biology Program and Department of Surgery, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115
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  • For correspondence: don.ingber@wyss.harvard.edu
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  • Supplementary Movie 1A[supplements/039917_file02.mp4]
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Posted April 15, 2020.
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Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics
Longlong Si, Haiqing Bai, Melissa Rodas, Wuji Cao, Crystal Yuri Oh, Amanda Jiang, Atiq Nurani, Danni Y. Zhu, Girija Goyal, Sarah E. Gilpin, Rachelle Prantil-Baun, Donald E. Ingber
bioRxiv 2020.04.13.039917; doi: https://doi.org/10.1101/2020.04.13.039917
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Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics
Longlong Si, Haiqing Bai, Melissa Rodas, Wuji Cao, Crystal Yuri Oh, Amanda Jiang, Atiq Nurani, Danni Y. Zhu, Girija Goyal, Sarah E. Gilpin, Rachelle Prantil-Baun, Donald E. Ingber
bioRxiv 2020.04.13.039917; doi: https://doi.org/10.1101/2020.04.13.039917

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