Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts

New Results

Jeffrey J. Quinn, Matthew G. Jones, Ross A. Okimoto, Shigeki Nanjo, Michelle M. Chan, Nir Yosef, Trever G. Bivona, Jonathan S. Weissman

doi: https://doi.org/10.1101/2020.04.16.045245

Jeffrey J. Quinn

1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA

2Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA

Matthew G. Jones

1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA

2Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA

3Biological and Medical Informatics Graduate Program, University of California, San Francisco, San Francisco, CA, USA

4Integrative Program in Quantitative Biology, University of California, San Francisco, San Francisco, CA, USA

10Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA

Ross A. Okimoto

5UCSF Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

6Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA

Shigeki Nanjo

5UCSF Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

6Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA

Michelle M. Chan

1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA

2Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA

Nir Yosef

7Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA

8Chan Zuckerberg Biohub Investigator, San Francisco, CA, USA

9Ragon Institute of Massachusetts General Hospital, MIT and Harvard University, Cambridge, MA, USA

10Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: weissman@wi.mit.edu Trever.Bivona@ucsf.edu niryosef@berkeley.edu

Trever G. Bivona

1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA

5UCSF Department of Medicine, University of California, San Francisco, San Francisco, CA, USA

6Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: weissman@wi.mit.edu Trever.Bivona@ucsf.edu niryosef@berkeley.edu

Jonathan S. Weissman

1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA

2Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA

11Whitehead Institute, Cambridge, MA, USA

12Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: weissman@wi.mit.edu Trever.Bivona@ucsf.edu niryosef@berkeley.edu