Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity

Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, View ORCID ProfileCharles Brenner
doi: https://doi.org/10.1101/2020.04.17.047480
Collin D. Heer
aFree Radical and Radiation Biology Program, University of Iowa, United States
bDepartment of Biochemistry, University of Iowa, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel J. Sanderson
cDepartment of Chemical Physiology & Biochemistry, Oregon Health Sciences University, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yousef M.O. Alhammad
dDepartment of Molecular Biosciences, University of Kansas, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mark S. Schmidt
bDepartment of Biochemistry, University of Iowa, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Samuel A.J. Trammell
bDepartment of Biochemistry, University of Iowa, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stanley Perlman
eDepartment of Microbiology & Immunology, University of Iowa, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael S. Cohen
cDepartment of Chemical Physiology & Biochemistry, Oregon Health Sciences University, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anthony R. Fehr
dDepartment of Molecular Biosciences, University of Kansas, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: arfehr@ku.edu charles-brenner@uiowa.edu
Charles Brenner
bDepartment of Biochemistry, University of Iowa, United States
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Charles Brenner
  • For correspondence: arfehr@ku.edu charles-brenner@uiowa.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Article Information

doi 
https://doi.org/10.1101/2020.04.17.047480
History 
  • April 18, 2020.

Article Versions

  • You are currently viewing Version 1 of this article (April 18, 2020 - 16:39).
  • Version 2 (April 18, 2020 - 22:57).
  • Version 3 (April 19, 2020 - 22:36).
  • Version 4 (April 30, 2020 - 19:30).
  • Version 5 (July 8, 2020 - 11:30).
  • View Version 6, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Collin D. Heera,b,
  2. Daniel J. Sandersonc,&,
  3. Yousef M.O. Alhammadd,&,
  4. Mark S. Schmidtb,&,
  5. Samuel A.J. Trammellb,*,
  6. Stanley Perlmane,
  7. Michael S. Cohenc,
  8. Anthony R. Fehrd,# and
  9. Charles Brennerb,#
  1. aFree Radical and Radiation Biology Program, University of Iowa, United States
  2. bDepartment of Biochemistry, University of Iowa, United States
  3. cDepartment of Chemical Physiology & Biochemistry, Oregon Health Sciences University, United States
  4. dDepartment of Molecular Biosciences, University of Kansas, United States
  5. eDepartment of Microbiology & Immunology, University of Iowa, United States
  1. ↵#correspondence to arfehr{at}ku.edu and charles-brenner{at}uiowa.edu
  1. ↵& equal contributions

  • ↵* Novo Nordisk Foundation, Center for Basic Metabolic Research, University of Copenhagen, Denmark

Back to top
PreviousNext
Posted April 18, 2020.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity
Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, Charles Brenner
bioRxiv 2020.04.17.047480; doi: https://doi.org/10.1101/2020.04.17.047480
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity
Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, Charles Brenner
bioRxiv 2020.04.17.047480; doi: https://doi.org/10.1101/2020.04.17.047480

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Microbiology
Subject Areas
All Articles
  • Animal Behavior and Cognition (4397)
  • Biochemistry (9632)
  • Bioengineering (7123)
  • Bioinformatics (24940)
  • Biophysics (12671)
  • Cancer Biology (9998)
  • Cell Biology (14405)
  • Clinical Trials (138)
  • Developmental Biology (7989)
  • Ecology (12148)
  • Epidemiology (2067)
  • Evolutionary Biology (16026)
  • Genetics (10953)
  • Genomics (14778)
  • Immunology (9907)
  • Microbiology (23739)
  • Molecular Biology (9508)
  • Neuroscience (51056)
  • Paleontology (370)
  • Pathology (1545)
  • Pharmacology and Toxicology (2694)
  • Physiology (4038)
  • Plant Biology (8696)
  • Scientific Communication and Education (1512)
  • Synthetic Biology (2404)
  • Systems Biology (6459)
  • Zoology (1350)