Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity

Collin D. Heer; Daniel J. Sanderson; Yousef M.O. Alhammad; Mark S. Schmidt; Samuel A.J. Trammell; Stanley Perlman; Michael S. Cohen; Anthony R. Fehr; Charles Brenner

doi:10.1101/2020.04.17.047480

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Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity

Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, View ORCID ProfileCharles Brenner

doi: https://doi.org/10.1101/2020.04.17.047480

Collin D. Heer

aFree Radical and Radiation Biology Program, University of Iowa, United States

bDepartment of Biochemistry, University of Iowa, United States

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Daniel J. Sanderson

cDepartment of Chemical Physiology & Biochemistry, Oregon Health Sciences University, United States

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Yousef M.O. Alhammad

dDepartment of Molecular Biosciences, University of Kansas, United States

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Mark S. Schmidt

bDepartment of Biochemistry, University of Iowa, United States

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Samuel A.J. Trammell

bDepartment of Biochemistry, University of Iowa, United States

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Stanley Perlman

eDepartment of Microbiology & Immunology, University of Iowa, United States

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Michael S. Cohen

cDepartment of Chemical Physiology & Biochemistry, Oregon Health Sciences University, United States

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Anthony R. Fehr

dDepartment of Molecular Biosciences, University of Kansas, United States

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For correspondence: arfehr@ku.edu charles-brenner@uiowa.edu

Charles Brenner

bDepartment of Biochemistry, University of Iowa, United States

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ORCID record for Charles Brenner
For correspondence: arfehr@ku.edu charles-brenner@uiowa.edu

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Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity

Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, Charles Brenner

bioRxiv 2020.04.17.047480; doi: https://doi.org/10.1101/2020.04.17.047480

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Coronavirus Infection and PARP Expression Dysregulate the NAD Metabolome: A Potentially Actionable Component of Innate Immunity

Collin D. Heer, Daniel J. Sanderson, Yousef M.O. Alhammad, Mark S. Schmidt, Samuel A.J. Trammell, Stanley Perlman, Michael S. Cohen, Anthony R. Fehr, Charles Brenner

bioRxiv 2020.04.17.047480; doi: https://doi.org/10.1101/2020.04.17.047480

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