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Neural correlates of cognitive motor signals in primary somatosensory cortex

Matiar Jafari, Tyson NS Aflalo, Srinivas Chivukula, Spencer S Kellis, Michelle Armenta Salas, Sumner L Norman, Kelsie Pejsa, Charles Y. Liu, Richard A Andersen
doi: https://doi.org/10.1101/2020.04.20.041269
Matiar Jafari
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
3UCLA-Caltech Medical Scientist Training Program, Los Angeles, United States
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Tyson NS Aflalo
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
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  • For correspondence: taflalo@caltech.edu
Srinivas Chivukula
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
4Department of Neurological Surgery, Los Angeles Medical Center, University of California, Los Angeles, Los Angeles, CA, United States
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Spencer S Kellis
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
5USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, United States
6Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, United States
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Michelle Armenta Salas
7Second Sight Medical Prod. Sylmar, CA, United States
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Sumner L Norman
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
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Kelsie Pejsa
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
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Charles Y. Liu
5USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, United States
6Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, United States
8Rancho Los Amigos National Rehabilitation Center, Downey, United States
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Richard A Andersen
1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
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Article Information

doi 
https://doi.org/10.1101/2020.04.20.041269
History 
  • April 21, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Matiar Jafari†,1,2,3,
  2. Tyson NS Aflalo†,1,2,‡,
  3. Srinivas Chivukula1,4,
  4. Spencer S Kellis1,2,5,6,
  5. Michelle Armenta Salas7,
  6. Sumner L Norman1,2,
  7. Kelsie Pejsa1,2,
  8. Charles Y. Liu5,6,8 and
  9. Richard A Andersen1,2
  1. 1Department of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States
  2. 2Tianqiao and Chrissy Chen Brain-Machine Interface Center, Chen Institute for Neuroscience, California Institute of Technology, Pasadena, United States
  3. 3UCLA-Caltech Medical Scientist Training Program, Los Angeles, United States
  4. 4Department of Neurological Surgery, Los Angeles Medical Center, University of California, Los Angeles, Los Angeles, CA, United States
  5. 5USC Neurorestoration Center, Keck School of Medicine of USC, Los Angeles, United States
  6. 6Department of Neurological Surgery, Keck School of Medicine of USC, Los Angeles, United States
  7. 7Second Sight Medical Prod. Sylmar, CA, United States
  8. 8Rancho Los Amigos National Rehabilitation Center, Downey, United States
  1. ↵‡Correspondence to taflalo{at}caltech.edu.
  1. ↵† Contributed Equally

  2. Contributions: M.J., T.A, and R.A.A designed the study, M.J. and T.A developed experimental tasks, M.J. and T.A. designed analysis and analyzed the data, M.J., S.C., S.S.K, and M.A.S. collected the data, S.L.N contributed code, M.J. and T.A. interpreted results and wrote the original draft, M.J., T.A., S.C., and R.A.A. reviewed and edited the paper, T.A. and R.A.A. provided mentorship, T.A., S.K., and R.A.A. acquired funding, K.P provided administrative and regulatory assistance, C.Y.L. performed implantation surgery.

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Posted April 21, 2020.
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Neural correlates of cognitive motor signals in primary somatosensory cortex
Matiar Jafari, Tyson NS Aflalo, Srinivas Chivukula, Spencer S Kellis, Michelle Armenta Salas, Sumner L Norman, Kelsie Pejsa, Charles Y. Liu, Richard A Andersen
bioRxiv 2020.04.20.041269; doi: https://doi.org/10.1101/2020.04.20.041269
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Neural correlates of cognitive motor signals in primary somatosensory cortex
Matiar Jafari, Tyson NS Aflalo, Srinivas Chivukula, Spencer S Kellis, Michelle Armenta Salas, Sumner L Norman, Kelsie Pejsa, Charles Y. Liu, Richard A Andersen
bioRxiv 2020.04.20.041269; doi: https://doi.org/10.1101/2020.04.20.041269

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