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Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion
View ORCID ProfileEleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Alejandra Tomas, Fiona Yong Su Wern, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Amelia K. Linnemann, View ORCID ProfileTristan A. Rodriguez, View ORCID ProfileGuy A. Rutter
doi: https://doi.org/10.1101/2020.04.22.055384
Eleni Georgiadou
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Charanya Muralidharan
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Michelle Martinez
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Pauline Chabosseau
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Alejandra Tomas
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Fiona Yong Su Wern
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
Theodoros Stylianides
4Loughborough University, Centre of Innovative and Collaborative Construction Engineering, Leicestershire, LE11 3TU, UK
Asger Wretlind
5Systems Medicin, Steno Diabetes Center Copenhagen, 2820, Denmark
Cristina Legido-Quigley
5Systems Medicin, Steno Diabetes Center Copenhagen, 2820, Denmark
6Institute of Pharmaceutical Science, Kings College London, London, SE1 9NH, UK
Nour Alsabeeh
7Kuwait University, Department of Physiology, Health Sciences Center, 13110, Kuwait
Céline Cruciani-Guglielmacci
8Université de Paris, BFA, UMR 8251, CNRS, Regulation of Glycemia by Central Nervous System, Paris, 75205, France
Christophe Magnan
8Université de Paris, BFA, UMR 8251, CNRS, Regulation of Glycemia by Central Nervous System, Paris, 75205, France
Mark Ibberson
9Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, CH-1015, Switzerland
Isabelle Leclerc
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Yusuf Ali
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
Amelia K. Linnemann
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Tristan A. Rodriguez
10National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, W12 0NN, UK
Guy A. Rutter
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
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Posted January 12, 2021.
Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion
Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Alejandra Tomas, Fiona Yong Su Wern, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Amelia K. Linnemann, Tristan A. Rodriguez, Guy A. Rutter
bioRxiv 2020.04.22.055384; doi: https://doi.org/10.1101/2020.04.22.055384
Mitofusins Mfn1 and Mfn2 are required in the β-cell to preserve mitochondrial architecture and insulin secretion
Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Alejandra Tomas, Fiona Yong Su Wern, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Amelia K. Linnemann, Tristan A. Rodriguez, Guy A. Rutter
bioRxiv 2020.04.22.055384; doi: https://doi.org/10.1101/2020.04.22.055384
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