New Results
Mitofusins Mfn1 and Mfn2 are required to preserve glucose-but not incretin- stimulated beta cell connectivity and insulin secretion
View ORCID ProfileEleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, View ORCID ProfileAlejandra Tomas, Fiona Yong Su Wern, Elina Akalestou, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Ben Jones, Livia Lopez Noriega, Yanwen Xu, Guoqiang Gu, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, View ORCID ProfileScott A. Soleimanpour, Amelia K. Linnemann, View ORCID ProfileTristan A. Rodriguez, View ORCID ProfileGuy A. Rutter
doi: https://doi.org/10.1101/2020.04.22.055384
Eleni Georgiadou
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Charanya Muralidharan
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Michelle Martinez
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Pauline Chabosseau
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Alejandra Tomas
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Fiona Yong Su Wern
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
Elina Akalestou
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Theodoros Stylianides
4Loughborough University, Centre of Innovative and Collaborative Construction Engineering, Leicestershire, LE11 3TU, UK
Asger Wretlind
5Systems Medicin, Steno Diabetes Center Copenhagen, 2820, Denmark
Cristina Legido-Quigley
5Systems Medicin, Steno Diabetes Center Copenhagen, 2820, Denmark
6Institute of Pharmaceutical Science, Kings College London, London, SE1 9NH, UK
Ben Jones
7Section of Endocrinology and Investigative Medicine, Imperial College London, W12 0NN,UK
Livia Lopez Noriega
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Yanwen Xu
8Department of Cell and Developmental Biology, Program of Developmental Biology, and Vanderbilt Center for Stem Cell Biology. Vanderbilt University, School of Medicine, Nashville, TN, 37232, USA.
Guoqiang Gu
8Department of Cell and Developmental Biology, Program of Developmental Biology, and Vanderbilt Center for Stem Cell Biology. Vanderbilt University, School of Medicine, Nashville, TN, 37232, USA.
Nour Alsabeeh
9Kuwait University, Department of Physiology, Health Sciences Center, 13110, Kuwait
Céline Cruciani-Guglielmacci
10Université de Paris, BFA, UMR 8251, CNRS, Regulation of Glycemia by Central Nervous System, Paris, 75205, France
Christophe Magnan
10Université de Paris, BFA, UMR 8251, CNRS, Regulation of Glycemia by Central Nervous System, Paris, 75205, France
Mark Ibberson
11Vital-IT Group, SIB Swiss Institute of Bioinformatics, Lausanne, CH-1015, Switzerland
Isabelle Leclerc
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
Yusuf Ali
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
Scott A. Soleimanpour
12Division of Metabolism, Endocrinology & Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA
13VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA
Amelia K. Linnemann
2Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, 46202, USA
Tristan A. Rodriguez
14National Heart and Lung Institute, Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, W12 0NN, UK
Guy A. Rutter
1Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, W12 0NN, UK
3Lee Kong Chian School of Medicine, Nanyang Technological University, 637553, Singapore
15Centre of research of CHUM, University of Montreal, Quebec, H2X 0A9, Canada
Article usage
Posted August 13, 2021.
Mitofusins Mfn1 and Mfn2 are required to preserve glucose-but not incretin- stimulated beta cell connectivity and insulin secretion
Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Alejandra Tomas, Fiona Yong Su Wern, Elina Akalestou, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Ben Jones, Livia Lopez Noriega, Yanwen Xu, Guoqiang Gu, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Scott A. Soleimanpour, Amelia K. Linnemann, Tristan A. Rodriguez, Guy A. Rutter
bioRxiv 2020.04.22.055384; doi: https://doi.org/10.1101/2020.04.22.055384
Mitofusins Mfn1 and Mfn2 are required to preserve glucose-but not incretin- stimulated beta cell connectivity and insulin secretion
Eleni Georgiadou, Charanya Muralidharan, Michelle Martinez, Pauline Chabosseau, Alejandra Tomas, Fiona Yong Su Wern, Elina Akalestou, Theodoros Stylianides, Asger Wretlind, Cristina Legido-Quigley, Ben Jones, Livia Lopez Noriega, Yanwen Xu, Guoqiang Gu, Nour Alsabeeh, Céline Cruciani-Guglielmacci, Christophe Magnan, Mark Ibberson, Isabelle Leclerc, Yusuf Ali, Scott A. Soleimanpour, Amelia K. Linnemann, Tristan A. Rodriguez, Guy A. Rutter
bioRxiv 2020.04.22.055384; doi: https://doi.org/10.1101/2020.04.22.055384
Subject Area
Subject Areas
- Biochemistry (11739)
- Bioengineering (8750)
- Bioinformatics (29189)
- Biophysics (14967)
- Cancer Biology (12093)
- Cell Biology (17409)
- Clinical Trials (138)
- Developmental Biology (9419)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18301)
- Genetics (12238)
- Genomics (16797)
- Immunology (11865)
- Microbiology (28068)
- Molecular Biology (11583)
- Neuroscience (60953)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4957)
- Plant Biology (10425)
- Synthetic Biology (2884)
- Systems Biology (7338)
- Zoology (1651)