Article Information
History
- April 27, 2020.
Article Versions
- You are currently viewing Version 1 of this article (April 27, 2020 - 23:42).
- View Version 2, the most recent version of this article.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Author Information
- Lu Zhang1,2,*,
- Dong Zhang1,2,
- Congmin Yuan3,4,
- Xiaowei Wang3,4,
- Yongfang Li1,2,
- Xilin Jia1,2,
- Xin Gao5,
- Hui-Ling Yen6,*,
- Peter Pak-Hang Cheung3,4,* and
- Xuhui Huang3,4,*
- 1State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian, China
- 2University of Chinese Academy of Sciences, Beijing, China
- 3Department of Chemistry, Centre of Systems Biology and Human Health, State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Kowloon, Hong Kong
- 4The Hong Kong University of Science and Technology-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen 518057, China
- 5Computational Bioscience Research Center, Computer, Electrical and Mathematical Sciences Engineering Division, King Abdullah University of Science and Technology, Saudi Arabia
- 6School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong
- ↵*correspondence could be addressed to: luzhang{at}fjirsm.ac.cn (L. Z.) or hyen{at}hku.hk (H.-L. Y.) or ppcheung{at}ust.hk (P. P.-H. C.) or xuhuihuang{at}ust.hk (X. H.)
Posted April 27, 2020.
Role of 1’-Ribose Cyano Substitution for Remdesivir to Effectively Inhibit both Nucleotide Addition and Proofreading in SARS-CoV-2 Viral RNA Replication
