Article Information
History
- April 29, 2020.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Yuki Oiwa1,2,
- Kaori Oka1,
- Hironobu Yasui3,4,
- Kei Higashikawa4,5,
- Hidemasa Bono6,
- Yoshimi Kawamura1,
- Shingo Miyawaki7,
- Akiyuki Watarai8,9,
- Takefumi Kikusui8,
- Atsushi Shimizu10,
- Hideyuki Okano11,
- Yuji Kuge4,5,
- Kazuhiro Kimura12,
- Yuko Okamatsu-Ogura12,* and
- Kyoko Miura1,11,13,14,*
- 1Department of Aging and Longevity Research, Kumamoto University, Kumamoto 860-0811, Japan
- 2Division of Immunobiology, Institute for Genetic Medicine, Hokkaido University, Hokkaido 060-0815, Japan
- 3Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido 060-0818, Japan
- 4Central Institute of Isotope Science, Hokkaido University, Hokkaido 060-0815, Japan
- 5Laboratory of Integrated Molecular Imaging, Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Hokkaido 060-0815, Japan
- 6Program of Biomedical Science, Graduate School of Integrated Sciences for Life, Hiroshima University, 3-10-23 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-0046, Japan
- 7Laboratory of Epigenome Dynamics, Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, Osaka, 565-0871, Japan
- 8Companion Animal Research, School of Veterinary Medicine, Azabu University, Sagamihara 252-5201, Japan
- 9Laboratory of Behavioral Neuroscience, Institute for Quantitative Biosciences, The University of Tokyo, 113-0032, Tokyo, Japan
- 10Division of Biomedical Information Analysis, Iwate Tohoku Medical Megabank Organization, Disaster Reconstruction Center, Iwate Medical University, Shiwa 028-3694, Japan
- 11Department of Physiology, Keio University School of Medicine, Tokyo 160-8582, Japan
- 12Laboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido 060-0818, Japan
- 13Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto 860-8556, Japan
- ↵*Correspondence: miurak{at}kumamoto-u.ac.jp (K. M.), y-okamatsu{at}vetmed.hokudai.ac.jp (Y.O.-O.)