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LFA-1 signals to promote actin polymerization and upstream migration in T cells

Nathan H Roy, Sarah Hyun Ji Kim, Alexander Buffone Jr, Daniel Blumenthal, Bonnie Huang, Sangya Agarwal, Pamela L Schwartzberg, Daniel A Hammer, View ORCID ProfileJanis K Burkhardt
doi: https://doi.org/10.1101/2020.04.29.069302
Nathan H Roy
1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA
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Sarah Hyun Ji Kim
4Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, USA
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Alexander Buffone Jr
3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
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Daniel Blumenthal
1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA
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Bonnie Huang
5Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
6National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
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Sangya Agarwal
2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
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Pamela L Schwartzberg
5Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
6National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
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Daniel A Hammer
3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
4Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, USA
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Janis K Burkhardt
1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA
2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
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  • ORCID record for Janis K Burkhardt
  • For correspondence: jburkhar@pennmedicine.upenn.edu
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Article Information

doi 
https://doi.org/10.1101/2020.04.29.069302
History 
  • May 2, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Nathan H Roy1,
  2. Sarah Hyun Ji Kim4,
  3. Alexander Buffone Jr3,
  4. Daniel Blumenthal1,
  5. Bonnie Huang5,6,
  6. Sangya Agarwal2,
  7. Pamela L Schwartzberg5,6,
  8. Daniel A Hammer3,4 and
  9. Janis K Burkhardt1,2,*
  1. 1Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, Philadelphia, PA, USA
  2. 2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
  3. 3Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
  4. 4Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA, USA
  5. 5Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
  6. 6National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
  1. ↵*Correspondence: Janis K. Burkhardt, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia Research Institute, 3615 Civic Center Blvd, ARC 815D, Philadelphia, PA 19104, USA, Tel: 267-426-5410, E-mail: jburkhar{at}pennmedicine.upenn.edu
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Posted May 02, 2020.
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LFA-1 signals to promote actin polymerization and upstream migration in T cells
Nathan H Roy, Sarah Hyun Ji Kim, Alexander Buffone Jr, Daniel Blumenthal, Bonnie Huang, Sangya Agarwal, Pamela L Schwartzberg, Daniel A Hammer, Janis K Burkhardt
bioRxiv 2020.04.29.069302; doi: https://doi.org/10.1101/2020.04.29.069302
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LFA-1 signals to promote actin polymerization and upstream migration in T cells
Nathan H Roy, Sarah Hyun Ji Kim, Alexander Buffone Jr, Daniel Blumenthal, Bonnie Huang, Sangya Agarwal, Pamela L Schwartzberg, Daniel A Hammer, Janis K Burkhardt
bioRxiv 2020.04.29.069302; doi: https://doi.org/10.1101/2020.04.29.069302

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