Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling

Jason J. Gokey; John Snowball; Jenna Green; Marion Waltamath; Jillian J. Spinney; Katharine E. Black; Lida P. Hariri; Yan Xu; Anne-Karina T. Perl

doi:10.1101/2020.05.06.080994

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Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling

Jason J. Gokey, John Snowball, Jenna Green, Marion Waltamath, Jillian J. Spinney, Katharine E. Black, Lida P. Hariri, Yan Xu, Anne-Karina T. Perl

doi: https://doi.org/10.1101/2020.05.06.080994

Jason J. Gokey

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

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John Snowball

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

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Jenna Green

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

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Marion Waltamath

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

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Jillian J. Spinney

4Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Katharine E. Black

4Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Lida P. Hariri

4Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

5Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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Yan Xu

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

2Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

3Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH

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Anne-Karina T. Perl

1The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

3Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH

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For correspondence: anne.perl@cchmc.org

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Posted May 08, 2020.

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Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling

Jason J. Gokey, John Snowball, Jenna Green, Marion Waltamath, Jillian J. Spinney, Katharine E. Black, Lida P. Hariri, Yan Xu, Anne-Karina T. Perl

bioRxiv 2020.05.06.080994; doi: https://doi.org/10.1101/2020.05.06.080994

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Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling

Jason J. Gokey, John Snowball, Jenna Green, Marion Waltamath, Jillian J. Spinney, Katharine E. Black, Lida P. Hariri, Yan Xu, Anne-Karina T. Perl

bioRxiv 2020.05.06.080994; doi: https://doi.org/10.1101/2020.05.06.080994

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