TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage

Marta Gianini; Daisy Sproviero; Aleix Bayona-Feliu; Cristina Cereda; Andrés Aguilera

doi:10.1101/2020.05.10.086652

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TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage

Marta Gianini, Daisy Sproviero, Aleix Bayona-Feliu, View ORCID ProfileCristina Cereda, View ORCID ProfileAndrés Aguilera

doi: https://doi.org/10.1101/2020.05.10.086652

Marta Gianini

1Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy

2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy

3Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain

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Daisy Sproviero

1Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy

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Aleix Bayona-Feliu

3Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain

4Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Seville, Spain

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Cristina Cereda

1Genomic and Post-Genomic Center, IRCCS Mondino Foundation, Pavia, Italy

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ORCID record for Cristina Cereda
For correspondence: cristina.cereda@mondino.it aguilo@us.es

Andrés Aguilera

3Andalusian Center of Molecular Biology and Regenerative Medicine-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide, Seville, Spain

4Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Seville, Spain

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For correspondence: cristina.cereda@mondino.it aguilo@us.es

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Posted May 10, 2020.

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TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage

Marta Gianini, Daisy Sproviero, Aleix Bayona-Feliu, Cristina Cereda, Andrés Aguilera

bioRxiv 2020.05.10.086652; doi: https://doi.org/10.1101/2020.05.10.086652

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TDP-43 deficiency links Amyotrophic Lateral Sclerosis with R-loop homeostasis and R loop-mediated DNA damage

Marta Gianini, Daisy Sproviero, Aleix Bayona-Feliu, Cristina Cereda, Andrés Aguilera

bioRxiv 2020.05.10.086652; doi: https://doi.org/10.1101/2020.05.10.086652

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