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Low doses of radiation therapy increase the immunosuppressive profile of lung macrophages via IL-10 production and IFNγ/IL-6 suppression: a therapeutic strategy to counteract lung inflammation?

View ORCID ProfileLydia Meziani, Charlotte Robert, Pierre Mordant, Eric Deutsch
doi: https://doi.org/10.1101/2020.05.11.077651
Lydia Meziani
1INSERM U1030, Radiothérapie Moléculaire et Innovations Thérapetuiques, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France
2Labex LERMIT, DHU TORINO, SIRIC SOCRATE
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  • ORCID record for Lydia Meziani
Charlotte Robert
1INSERM U1030, Radiothérapie Moléculaire et Innovations Thérapetuiques, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France
2Labex LERMIT, DHU TORINO, SIRIC SOCRATE
3Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France
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Pierre Mordant
4Department of vascular surgery, thoracic surgery, and lung transplantation, Bichat Hospital, Assistance Publique – Hôpitaux de Paris, INSERM U1152, Université de Paris, Paris, France
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Eric Deutsch
1INSERM U1030, Radiothérapie Moléculaire et Innovations Thérapetuiques, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France
2Labex LERMIT, DHU TORINO, SIRIC SOCRATE
3Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France
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  • For correspondence: eric.deutsch@gustaveroussy.fr lydia.meziani@gustaveroussy.fr
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Posted May 13, 2020.
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Low doses of radiation therapy increase the immunosuppressive profile of lung macrophages via IL-10 production and IFNγ/IL-6 suppression: a therapeutic strategy to counteract lung inflammation?
Lydia Meziani, Charlotte Robert, Pierre Mordant, Eric Deutsch
bioRxiv 2020.05.11.077651; doi: https://doi.org/10.1101/2020.05.11.077651
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Low doses of radiation therapy increase the immunosuppressive profile of lung macrophages via IL-10 production and IFNγ/IL-6 suppression: a therapeutic strategy to counteract lung inflammation?
Lydia Meziani, Charlotte Robert, Pierre Mordant, Eric Deutsch
bioRxiv 2020.05.11.077651; doi: https://doi.org/10.1101/2020.05.11.077651

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