Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia

Lydia Meziani; Charlotte Robert; Marion Classe; Bruno Da Costa; Michele Mondini; Céline Clemenson; Pierre Mordant; Samy Ammari; Ronan Le Goffic; Eric Deutsch

doi:10.1101/2020.05.11.077651

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Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia

View ORCID ProfileLydia Meziani, Charlotte Robert, Marion Classe, Bruno Da Costa, Michele Mondini, Céline Clemenson, Pierre Mordant, Samy Ammari, Ronan Le Goffic, Eric Deutsch

doi: https://doi.org/10.1101/2020.05.11.077651

Lydia Meziani

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

2Labex LERMIT, DHU TORINO, SIRIC SOCRATE

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ORCID record for Lydia Meziani
For correspondence: eric.deutsch@gustaveroussy.fr lydia.meziani@gustaveroussy.fr

Charlotte Robert

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

2Labex LERMIT, DHU TORINO, SIRIC SOCRATE

3Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France

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Marion Classe

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

4Department of Pathology, Gustave Roussy Cancer Campus, Villejuif, France

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Bruno Da Costa

5Université Paris-Saclay, INRAE, UVSQ, VIM, 78350 Jouy-en-Josas, France

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Michele Mondini

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

2Labex LERMIT, DHU TORINO, SIRIC SOCRATE

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Céline Clemenson

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

2Labex LERMIT, DHU TORINO, SIRIC SOCRATE

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Pierre Mordant

6Department of vascular surgery, thoracic surgery, and lung transplantation, Bichat Hospital, Assistance Publique – Hôpitaux de Paris, INSERM U1152, Université de Paris, Paris, France

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Samy Ammari

7Department of Radiology, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

8BioMaps (UMR1281), Université Paris-Saclay, CNRS. INSRRM. CEA, Orsay, 91471, France

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Ronan Le Goffic

5Université Paris-Saclay, INRAE, UVSQ, VIM, 78350 Jouy-en-Josas, France

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Eric Deutsch

1INSERM U1030, Molecular Radiotherapy and Therapeutic Innovation, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France

2Labex LERMIT, DHU TORINO, SIRIC SOCRATE

3Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France

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For correspondence: eric.deutsch@gustaveroussy.fr lydia.meziani@gustaveroussy.fr

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Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia

Lydia Meziani, Charlotte Robert, Marion Classe, Bruno Da Costa, Michele Mondini, Céline Clemenson, Pierre Mordant, Samy Ammari, Ronan Le Goffic, Eric Deutsch

bioRxiv 2020.05.11.077651; doi: https://doi.org/10.1101/2020.05.11.077651

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Low doses of radiation increase the immunosuppressive profile of lung macrophages during viral infection and pneumonia

Lydia Meziani, Charlotte Robert, Marion Classe, Bruno Da Costa, Michele Mondini, Céline Clemenson, Pierre Mordant, Samy Ammari, Ronan Le Goffic, Eric Deutsch

bioRxiv 2020.05.11.077651; doi: https://doi.org/10.1101/2020.05.11.077651

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