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SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant
Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Masaya Fukushi, Takashi Irie, Yoshio Koyanagi, So Nakagawa, Kei Sato
doi: https://doi.org/10.1101/2020.05.11.088179
Yoriyuki Konno
1Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, the University of Tokyo, Tokyo 1088639, Japan
Izumi Kimura
1Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, the University of Tokyo, Tokyo 1088639, Japan
Keiya Uriu
1Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, the University of Tokyo, Tokyo 1088639, Japan
2Graduate School of Medicine, the University of Tokyo, Tokyo 1130033, Japan
Masaya Fukushi
3Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 7398511, Japan
Takashi Irie
3Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima 7398511, Japan
Yoshio Koyanagi
4Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 6068507, Japan
So Nakagawa
5Department of Molecular Life Science, Tokai University School of Medicine, Kanagawa 2591193, Japan
Kei Sato
1Division of Systems Virology, Department of Infectious Disease Control, International Research Center for Infectious Diseases, Institute of Medical Science, the University of Tokyo, Tokyo 1088639, Japan

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Posted May 12, 2020.
SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant
Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Masaya Fukushi, Takashi Irie, Yoshio Koyanagi, So Nakagawa, Kei Sato
bioRxiv 2020.05.11.088179; doi: https://doi.org/10.1101/2020.05.11.088179
SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant
Yoriyuki Konno, Izumi Kimura, Keiya Uriu, Masaya Fukushi, Takashi Irie, Yoshio Koyanagi, So Nakagawa, Kei Sato
bioRxiv 2020.05.11.088179; doi: https://doi.org/10.1101/2020.05.11.088179
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