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Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody
Wei Li, Aleksandra Drelich, David R. Martinez, Lisa Gralinski, Chuan Chen, Zehua Sun, Xianglei Liu, Doncho Zhelev, Liyong Zhang, Eric C. Peterson, Alex Conard, John W. Mellors, Chien-Te Tseng, Ralph S. Baric, Dimiter S. Dimitrov
doi: https://doi.org/10.1101/2020.05.13.093088
Wei Li
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Aleksandra Drelich
2Department of Microbiology & Immunology, Centers for Biodefense and Emerging Diseases, Galveston National Laboratory, 301 University Blvd, Galveston, Texas 77550, USA
David R. Martinez
3University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center Chapel Hill, NC 27599, USA
Lisa Gralinski
3University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center Chapel Hill, NC 27599, USA
Chuan Chen
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Zehua Sun
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Xianglei Liu
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Doncho Zhelev
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Liyong Zhang
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
Eric C. Peterson
4Abound Bio, 1401 Forbes Ave, Pittsburgh, PA 15219, USA
Alex Conard
4Abound Bio, 1401 Forbes Ave, Pittsburgh, PA 15219, USA
John W. Mellors
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
4Abound Bio, 1401 Forbes Ave, Pittsburgh, PA 15219, USA
Chien-Te Tseng
2Department of Microbiology & Immunology, Centers for Biodefense and Emerging Diseases, Galveston National Laboratory, 301 University Blvd, Galveston, Texas 77550, USA
Ralph S. Baric
3University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center Chapel Hill, NC 27599, USA
Dimiter S. Dimitrov
1Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace Str, Pittsburgh, PA 15261, USA
4Abound Bio, 1401 Forbes Ave, Pittsburgh, PA 15219, USA
Article usage
Posted May 14, 2020.
Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody
Wei Li, Aleksandra Drelich, David R. Martinez, Lisa Gralinski, Chuan Chen, Zehua Sun, Xianglei Liu, Doncho Zhelev, Liyong Zhang, Eric C. Peterson, Alex Conard, John W. Mellors, Chien-Te Tseng, Ralph S. Baric, Dimiter S. Dimitrov
bioRxiv 2020.05.13.093088; doi: https://doi.org/10.1101/2020.05.13.093088
Potent neutralization of SARS-CoV-2 in vitro and in an animal model by a human monoclonal antibody
Wei Li, Aleksandra Drelich, David R. Martinez, Lisa Gralinski, Chuan Chen, Zehua Sun, Xianglei Liu, Doncho Zhelev, Liyong Zhang, Eric C. Peterson, Alex Conard, John W. Mellors, Chien-Te Tseng, Ralph S. Baric, Dimiter S. Dimitrov
bioRxiv 2020.05.13.093088; doi: https://doi.org/10.1101/2020.05.13.093088
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