New Results
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
A. Shannon, B. Selisko, NTT Le, J. Huchting, F. Touret, G. Piorkowski, V. Fattorini, View ORCID ProfileF. Ferron, View ORCID ProfileE. Decroly, View ORCID ProfileC Meier, View ORCID ProfileB. Coutard, View ORCID ProfileO. Peersen, View ORCID ProfileB. Canard
doi: https://doi.org/10.1101/2020.05.15.098731
A. Shannon
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
B. Selisko
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
NTT Le
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
J. Huchting
2University of Hamburg, Faculty of Sciences, Department of Chemistry, Organic Chemistry, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany
F. Touret
3Unité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France
G. Piorkowski
3Unité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France
V. Fattorini
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
F. Ferron
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
E. Decroly
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
C Meier
2University of Hamburg, Faculty of Sciences, Department of Chemistry, Organic Chemistry, Martin-Luther-King-Platz 6, D-20146 Hamburg, Germany
B. Coutard
3Unité des Virus Émergents (UVE: Aix-Marseille Univ - IRD 190 - Inserm 1207 - IHU Méditerranée Infection), Marseille, France
O. Peersen
4Department of Biochemistry & Molecular Biology, Colorado State University, Fort Collins, CO 80523-1870, USA
B. Canard
1Architecture et Fonction des Macromolécules Biologiques, CNRS and Aix-Marseille Université, UMR 7257, Polytech Case 925, 13009 Marseille, France
Posted May 15, 2020.
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
A. Shannon, B. Selisko, NTT Le, J. Huchting, F. Touret, G. Piorkowski, V. Fattorini, F. Ferron, E. Decroly, C Meier, B. Coutard, O. Peersen, B. Canard
bioRxiv 2020.05.15.098731; doi: https://doi.org/10.1101/2020.05.15.098731
Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase
A. Shannon, B. Selisko, NTT Le, J. Huchting, F. Touret, G. Piorkowski, V. Fattorini, F. Ferron, E. Decroly, C Meier, B. Coutard, O. Peersen, B. Canard
bioRxiv 2020.05.15.098731; doi: https://doi.org/10.1101/2020.05.15.098731
Subject Area
Subject Areas
- Biochemistry (11571)
- Bioengineering (8622)
- Bioinformatics (28868)
- Biophysics (14803)
- Cancer Biology (11941)
- Cell Biology (17168)
- Clinical Trials (138)
- Developmental Biology (9302)
- Ecology (14019)
- Epidemiology (2067)
- Evolutionary Biology (18128)
- Genetics (12145)
- Genomics (16616)
- Immunology (11707)
- Microbiology (27692)
- Molecular Biology (11387)
- Neuroscience (60096)
- Paleontology (447)
- Pathology (1847)
- Pharmacology and Toxicology (3184)
- Physiology (4878)
- Plant Biology (10278)
- Synthetic Biology (2849)
- Systems Biology (7289)
- Zoology (1619)