New Results
Tractor: A framework allowing for improved inclusion of admixed individuals in large-scale association studies
View ORCID ProfileElizabeth G. Atkinson, View ORCID ProfileAdam X. Maihofer, View ORCID ProfileMasahiro Kanai, View ORCID ProfileAlicia R. Martin, View ORCID ProfileKonrad J. Karczewski, View ORCID ProfileMarcos L. Santoro, View ORCID ProfileJacob C. Ulirsch, Yoichiro Kamatani, Yukinori Okada, View ORCID ProfileHilary K. Finucane, View ORCID ProfileKarestan C. Koenen, View ORCID ProfileCaroline M. Nievergelt, View ORCID ProfileMark J. Daly, View ORCID ProfileBenjamin M. Neale
doi: https://doi.org/10.1101/2020.05.17.100727
Elizabeth G. Atkinson
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Adam X. Maihofer
4Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Masahiro Kanai
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
5Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, USA
6Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan
Alicia R. Martin
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Konrad J. Karczewski
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Marcos L. Santoro
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
7Departamento de Psiquiatria, Universidade Federal de São Paulo, São Paulo, Brazil
Jacob C. Ulirsch
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
8Program in Biological and Biomedical Science, Harvard Medical School, Boston, MA, USA
Yoichiro Kamatani
9Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
Yukinori Okada
6Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan
10Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan
11Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan
Hilary K. Finucane
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Karestan C. Koenen
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
12Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA
Caroline M. Nievergelt
4Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Mark J. Daly
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
3Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA
13Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland
Benjamin M. Neale
1Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
2Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Posted May 19, 2020.
Tractor: A framework allowing for improved inclusion of admixed individuals in large-scale association studies
Elizabeth G. Atkinson, Adam X. Maihofer, Masahiro Kanai, Alicia R. Martin, Konrad J. Karczewski, Marcos L. Santoro, Jacob C. Ulirsch, Yoichiro Kamatani, Yukinori Okada, Hilary K. Finucane, Karestan C. Koenen, Caroline M. Nievergelt, Mark J. Daly, Benjamin M. Neale
bioRxiv 2020.05.17.100727; doi: https://doi.org/10.1101/2020.05.17.100727
Tractor: A framework allowing for improved inclusion of admixed individuals in large-scale association studies
Elizabeth G. Atkinson, Adam X. Maihofer, Masahiro Kanai, Alicia R. Martin, Konrad J. Karczewski, Marcos L. Santoro, Jacob C. Ulirsch, Yoichiro Kamatani, Yukinori Okada, Hilary K. Finucane, Karestan C. Koenen, Caroline M. Nievergelt, Mark J. Daly, Benjamin M. Neale
bioRxiv 2020.05.17.100727; doi: https://doi.org/10.1101/2020.05.17.100727
Subject Area
Subject Areas
- Biochemistry (11753)
- Bioengineering (8752)
- Bioinformatics (29201)
- Biophysics (14974)
- Cancer Biology (12100)
- Cell Biology (17413)
- Clinical Trials (138)
- Developmental Biology (9422)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18309)
- Genetics (12245)
- Genomics (16804)
- Immunology (11869)
- Microbiology (28098)
- Molecular Biology (11596)
- Neuroscience (60975)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)