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Learning is shaped by abrupt changes in neural engagement

View ORCID ProfileJay A. Hennig, Emily R. Oby, Matthew D. Golub, Lindsay A. Bahureksa, Patrick T. Sadtler, Kristin M. Quick, Stephen I. Ryu, Elizabeth C. Tyler-Kabara, Aaron P. Batista, Steven M. Chase, Byron M. Yu
doi: https://doi.org/10.1101/2020.05.24.112714
Jay A. Hennig
1Neuroscience Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
3Machine Learning Department, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
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  • ORCID record for Jay A. Hennig
  • For correspondence: jhennig@cmu.edu
Emily R. Oby
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
4Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
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Matthew D. Golub
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
5Department of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
6Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA
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Lindsay A. Bahureksa
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
7Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
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Patrick T. Sadtler
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
8Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
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Kristin M. Quick
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
8Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
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Stephen I. Ryu
6Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA
9Department of Neurosurgery, Palo Alto Medical Foundation, Palo Alto, California 94301, USA
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Elizabeth C. Tyler-Kabara
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
10Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
11Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
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Aaron P. Batista
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
8Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
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Steven M. Chase
1Neuroscience Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
7Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
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Byron M. Yu
1Neuroscience Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
5Department of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
7Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
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Article Information

doi 
https://doi.org/10.1101/2020.05.24.112714
History 
  • May 25, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jay A. Hennig1,2,3,†,
  2. Emily R. Oby2,4,
  3. Matthew D. Golub2,5,6,
  4. Lindsay A. Bahureksa2,7,
  5. Patrick T. Sadtler2,8,
  6. Kristin M. Quick2,8,
  7. Stephen I. Ryu6,9,
  8. Elizabeth C. Tyler-Kabara2,10,11,
  9. Aaron P. Batista2,8,*,
  10. Steven M. Chase1,2,7,* and
  11. Byron M. Yu1,2,5,7,*
  1. 1Neuroscience Institute, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
  2. 2Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USA
  3. 3Machine Learning Department, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
  4. 4Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
  5. 5Department of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
  6. 6Department of Electrical Engineering, Stanford University, Stanford, California 94305, USA
  7. 7Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
  8. 8Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
  9. 9Department of Neurosurgery, Palo Alto Medical Foundation, Palo Alto, California 94301, USA
  10. 10Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
  11. 11Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
  1. ↵†Correspondence: jhennig{at}cmu.edu
  1. ↵* These authors contributed equally to this work.

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Posted May 25, 2020.
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Learning is shaped by abrupt changes in neural engagement
Jay A. Hennig, Emily R. Oby, Matthew D. Golub, Lindsay A. Bahureksa, Patrick T. Sadtler, Kristin M. Quick, Stephen I. Ryu, Elizabeth C. Tyler-Kabara, Aaron P. Batista, Steven M. Chase, Byron M. Yu
bioRxiv 2020.05.24.112714; doi: https://doi.org/10.1101/2020.05.24.112714
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Learning is shaped by abrupt changes in neural engagement
Jay A. Hennig, Emily R. Oby, Matthew D. Golub, Lindsay A. Bahureksa, Patrick T. Sadtler, Kristin M. Quick, Stephen I. Ryu, Elizabeth C. Tyler-Kabara, Aaron P. Batista, Steven M. Chase, Byron M. Yu
bioRxiv 2020.05.24.112714; doi: https://doi.org/10.1101/2020.05.24.112714

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