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Enantiomers of Chloroquine and Hydroxychloroquine Exhibit Different Activities Against SARS-CoV-2 in vitro, Evidencing S-Hydroxychloroquine as a Potentially Superior Drug for COVID-19
View ORCID ProfileGuanguan Li, Jing Sun, Yingjun Li, Yongjie Shi, Jincun Zhao, Tony Y. Zhang, Xumu Zhang
doi: https://doi.org/10.1101/2020.05.26.114033
Guanguan Li
1Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
Jing Sun
3State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510182, China
Yingjun Li
1Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
2Medi-X, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
Yongjie Shi
1Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
Jincun Zhao
3State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510182, China
Tony Y. Zhang
4Tyligand Bioscience (Shanghai) Limited, Shanghai, China
Xumu Zhang
1Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Department of Chemistry, College of Science, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
2Medi-X, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangzhou 518055, China
Posted July 15, 2020.
Enantiomers of Chloroquine and Hydroxychloroquine Exhibit Different Activities Against SARS-CoV-2 in vitro, Evidencing S-Hydroxychloroquine as a Potentially Superior Drug for COVID-19
Guanguan Li, Jing Sun, Yingjun Li, Yongjie Shi, Jincun Zhao, Tony Y. Zhang, Xumu Zhang
bioRxiv 2020.05.26.114033; doi: https://doi.org/10.1101/2020.05.26.114033
Enantiomers of Chloroquine and Hydroxychloroquine Exhibit Different Activities Against SARS-CoV-2 in vitro, Evidencing S-Hydroxychloroquine as a Potentially Superior Drug for COVID-19
Guanguan Li, Jing Sun, Yingjun Li, Yongjie Shi, Jincun Zhao, Tony Y. Zhang, Xumu Zhang
bioRxiv 2020.05.26.114033; doi: https://doi.org/10.1101/2020.05.26.114033
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