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Functional microRNA targetome undergoes degeneration-induced shift in the retina

View ORCID ProfileJoshua A. Chu-Tan, Zhi-Ping Feng, Yvette Wooff, Adrian V. Cioanca, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
doi: https://doi.org/10.1101/2020.05.27.118307
Joshua A. Chu-Tan
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
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  • ORCID record for Joshua A. Chu-Tan
Zhi-Ping Feng
3The ANU Bioinformatics Consultancy, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
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Yvette Wooff
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
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Adrian V. Cioanca
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
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Ulrike Schumann
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
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Riemke Aggio-Bruce
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
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Hardip Patel
3The ANU Bioinformatics Consultancy, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
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Matt Rutar
4School of Biomedical Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia
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Katherine Hannan
5ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
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Konstantin Panov
6School of Biological Sciences, Queen’s University Belfast, Belfast BT9 5DL, Northern Ireland
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Jan Provis
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
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Riccardo Natoli
1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
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  • For correspondence: riccardo.natoli@anu.edu.au
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Article Information

doi 
https://doi.org/10.1101/2020.05.27.118307
History 
  • May 27, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Joshua A. Chu-Tan1,2,
  2. Zhi-Ping Feng3,
  3. Yvette Wooff1,2,
  4. Adrian V. Cioanca1,
  5. Ulrike Schumann1,
  6. Riemke Aggio-Bruce1,2,
  7. Hardip Patel3,
  8. Matt Rutar4,
  9. Katherine Hannan5,
  10. Konstantin Panov6,
  11. Jan Provis1,2 and
  12. Riccardo Natoli1,2,*
  1. 1Eccles Institute of Neuroscience, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
  2. 2The Australian National University Medical School, College of Health and Medicine, Acton, ACT 2601, Australia
  3. 3The ANU Bioinformatics Consultancy, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
  4. 4School of Biomedical Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia
  5. 5ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia
  6. 6School of Biological Sciences, Queen’s University Belfast, Belfast BT9 5DL, Northern Ireland
  1. ↵*Corresponding author: Riccardo Natoli, Clear Vision Research Laboratory, Eccles Institute of Neuroscience, John Curtin School of Medical Research, College of Health and Medicine, The Australian National University, Acton, ACT 2601, Australia, riccardo.natoli{at}anu.edu.au, +61 2 612 58559
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Posted May 27, 2020.
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Functional microRNA targetome undergoes degeneration-induced shift in the retina
Joshua A. Chu-Tan, Zhi-Ping Feng, Yvette Wooff, Adrian V. Cioanca, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
bioRxiv 2020.05.27.118307; doi: https://doi.org/10.1101/2020.05.27.118307
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Functional microRNA targetome undergoes degeneration-induced shift in the retina
Joshua A. Chu-Tan, Zhi-Ping Feng, Yvette Wooff, Adrian V. Cioanca, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
bioRxiv 2020.05.27.118307; doi: https://doi.org/10.1101/2020.05.27.118307

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