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A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders

Abolfazl Doostparast Torshizi, Jubao Duan, Kai Wang
doi: https://doi.org/10.1101/2020.05.28.121483
Abolfazl Doostparast Torshizi
1Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA
2Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
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Jubao Duan
3Center for Psychiatric Genetics, North Shore University Health System, Evanston, IL 60201, USA
4Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL 60015, USA
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Kai Wang
1Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA
2Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
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  • For correspondence: wangk@email.chop.edu
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Posted July 16, 2020.
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A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders
Abolfazl Doostparast Torshizi, Jubao Duan, Kai Wang
bioRxiv 2020.05.28.121483; doi: https://doi.org/10.1101/2020.05.28.121483
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A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders
Abolfazl Doostparast Torshizi, Jubao Duan, Kai Wang
bioRxiv 2020.05.28.121483; doi: https://doi.org/10.1101/2020.05.28.121483

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