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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Heming Wang, Raymond Noordam, Brian E Cade, Karen Schwander, Thomas W Winkler, Jiwon Lee, Yun Ju Sung, Amy R. Bentley, Alisa K Manning, Hugues Aschard, Tuomas O Kilpeläinen, Marjan Ilkov, Michael R Brown, Andrea R Horimoto, Melissa Richard, Traci M Bartz, Dina Vojinovic, Elise Lim, Jovia L Nierenberg, Yongmei Liu, Kumaraswamynaidu Chitrala, Tuomo Rankinen, Solomon K Musani, Nora Franceschini, Rainer Rauramaa, Maris Alver, Phyllis Zee, Sarah E Harris, Peter J van der Most, Ilja M Nolte, Patricia B Munroe, Nicholette D Palmer, Brigitte Kühnel, Stefan Weiss, Wanqing Wen, Kelly A Hall, Leo-Pekka Lyytikäinen, Jeff O’Connell, Gudny Eiriksdottir, Lenore J Launer, Paul S de Vries, Dan E Arking, Han Chen, Eric Boerwinkle, Jose E Krieger, Pamela J Schreiner, Stephen S Sidney, James M Shikany, Kenneth Rice, Yii-Der Ida Chen, Sina A Gharib, Joshua C Bis, Annemarie I Luik, M Arfan Ikram, André G Uitterlinden, Najaf Amin, Hanfei Xu, Daniel Levy, Jiang He, Kurt K Lohman, Alan B Zonderman, Treva K Rice, Mario Sims, Gregory Wilson, Tamar Sofer, Stephen S Rich, Walter Palmas, Jie Yao, Xiuqing Guo, Jerome I Rotter, Nienke R Biermasz, Dennis O Mook-Kanamori, Lisa W Martin, Ana Barac, Robert B Wallace, Daniel Gottlieb, Pirjo Komulainen, Sami Heikkinen, Reedik Mägi, Lili Milani, Andres Metspalu, John M Starr, Yuri Milaneschi, RJ Waken, Chuan Gao, Melanie Waldenberger, Annette Peters, Konstantin Strauch, Thomas Meitinger, Till Roenneberg, Uwe Völker, Marcus Dörr, Xiao-Ou Shu, Sutapa Mukherjee, David R Hillman, Mika Kähönen, Lynne E Wagenknecht, Christian Gieger, Hans J Grabe, Wei Zheng, Lyle J Palmer, Terho Lehtimäki, Vilmundur Gudnason, Alanna C Morrison, Alexandre C Pereira, Myriam Fornage, Bruce M Psaty, Cornelia M van Duijn, View ORCID ProfileChing-Ti Liu, Tanika N Kelly, Michele K Evans, Claude Bouchard, Ervin R Fox, Charles Kooperberg, Xiaofeng Zhu, Timo A Lakka, Tõnu Esko, Kari E North, Ian J Deary, Harold Snieder, Brenda WJH Penninx, James Gauderman, Dabeeru C Rao, Susan Redline, Diana van Heemst
doi: https://doi.org/10.1101/2020.05.29.123505
Heming Wang
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
2Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
Raymond Noordam
3Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333ZA, The Netherlands
Brian E Cade
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
2Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
Karen Schwander
4Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA
Thomas W Winkler
5Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany
Jiwon Lee
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Yun Ju Sung
4Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA
Amy R. Bentley
6Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Alisa K Manning
2Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
7Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Hugues Aschard
8Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
9Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France
Tuomas O Kilpeläinen
10Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark
11Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, New York, USA
Marjan Ilkov
12Icelandic Heart Association, Kopavogur 201, Iceland
Michael R Brown
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Andrea R Horimoto
14Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 5403000, Brazil
Melissa Richard
15Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA
Traci M Bartz
16Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA 98101, USA
Dina Vojinovic
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
18Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands
Elise Lim
19Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
Jovia L Nierenberg
20Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112 USA
Yongmei Liu
21Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute Duke University School of Medicine, Durham, NC 27701, USA
Kumaraswamynaidu Chitrala
22Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Tuomo Rankinen
23Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Solomon K Musani
24Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39213, USA
Nora Franceschini
25Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27516, USA
Rainer Rauramaa
26Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland
Maris Alver
27Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia
28Department of Genetic Medicine and Development, University of Geneva, Geneva 1211, Switzerland
Phyllis Zee
29Department of Neurology, Northwestern University, Chicago, IL, USA
Sarah E Harris
30Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK
Peter J van der Most
31Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, The Netherlands
Ilja M Nolte
31Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, The Netherlands
Patricia B Munroe
32Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK
33National Institute for Health Research Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, London EC1M 6BQ, UK
Nicholette D Palmer
34Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
Brigitte Kühnel
35Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
36Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
Stefan Weiss
37Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald 17489, Germany
38German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald 17475, Germany
Wanqing Wen
39Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Kelly A Hall
40School of Public Health, The University of Adelaide, Adelaide, South Australia 5005, Australia
Leo-Pekka Lyytikäinen
41Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland
42Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland
Jeff O’Connell
43Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA
44Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Gudny Eiriksdottir
12Icelandic Heart Association, Kopavogur 201, Iceland
Lenore J Launer
22Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Paul S de Vries
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Dan E Arking
45McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Han Chen
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
46Center for Precision Health, School of Public Health & School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Eric Boerwinkle
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
47Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA
Jose E Krieger
14Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 5403000, Brazil
Pamela J Schreiner
48Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Stephen S Sidney
49Kaiser Permanente Northern California, Oakland, CA, USA
James M Shikany
50Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Kenneth Rice
51Department of Biostatistics, University of Washington, Seattle, WA 98195, USA
Yii-Der Ida Chen
52The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA
Sina A Gharib
53Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Department of Medicine, University of Washington, Seattle, WA 98109, USA
Joshua C Bis
54Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA
Annemarie I Luik
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
M Arfan Ikram
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
55Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
André G Uitterlinden
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Najaf Amin
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Hanfei Xu
19Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
Daniel Levy
19Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
56Population Sciences Branch, National Heart, Lung, and Blood Institute Framingham Heart Study, Framingham, MA 01702, USA
Jiang He
20Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112 USA
Kurt K Lohman
21Division of Cardiology, Department of Medicine, Duke Molecular Physiology Institute Duke University School of Medicine, Durham, NC 27701, USA
Alan B Zonderman
22Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Treva K Rice
4Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA
Mario Sims
24Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39213, USA
Gregory Wilson
57JHS Graduate Training and Education Center, Jackson State University, Jackson, MS 39213, USA
Tamar Sofer
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
2Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
Stephen S Rich
58Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA
Walter Palmas
59Division of General Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA
Jie Yao
52The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA
Xiuqing Guo
52The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA
Jerome I Rotter
52The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA 90502, USA
Nienke R Biermasz
60Division of Endocrinology, Department of Internal Medicine, Leiden University Medical Center, Leiden 2333ZA, The Netherlands
Dennis O Mook-Kanamori
61Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333ZA, Netherlands
62Department of Public Health and Primary Care, Leiden University Medical Center, Leiden 2333ZA, The Netherlands
Lisa W Martin
63George Washington University School of Medicine and Health Sciences, Washington DC, USA
Ana Barac
64MedStar Heart and Vascular Institute, Washington DC, USA
Robert B Wallace
65Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA
Daniel Gottlieb
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
Pirjo Komulainen
26Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland
Sami Heikkinen
66Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland
67Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio 70211, Finland
Reedik Mägi
27Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia
Lili Milani
27Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia
Andres Metspalu
27Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia
John M Starr
68Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh EH8 9JZ, UK
Yuri Milaneschi
69Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam 1081 BT, The Netherlands
RJ Waken
70Field and Environmental Data Science, Benson Hill Inc., St. Louis, MO 63132, USA
Chuan Gao
71Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
Melanie Waldenberger
35Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
36Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
Annette Peters
36Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
72German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Neuherberg, Germany
Konstantin Strauch
73Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz 55101, Germany
74Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
Thomas Meitinger
75Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
Till Roenneberg
76Institute of Medical Psychology, Ludwig-Maximilians-Universität München, Munich 80336, Germany
Uwe Völker
37Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald 17489, Germany
38German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald 17475, Germany
Marcus Dörr
38German Center for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald 17475, Germany
77Department of Internal Medicine B, University Medicine Greifswald, Greifswald 17489, Germany
Xiao-Ou Shu
39Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Sutapa Mukherjee
78Sleep Health Service, Respiratory and Sleep Services, Southern Adelaide Local Health Network, Adelaide, South Australia 5042, Australia
79Adelaide Institute for Sleep Health, Flinders University, Adelaide, South Australia 5042, Australia
David R Hillman
80Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia 6009, Australia
Mika Kähönen
42Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland
81Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland
Lynne E Wagenknecht
82Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA
Christian Gieger
35Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany
83German Center for Diabetes Research (DZD e.V.), Neuherberg 85764, Germany
Hans J Grabe
84Department Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald 17489, Germany
Wei Zheng
39Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Lyle J Palmer
40School of Public Health, The University of Adelaide, Adelaide, South Australia 5005, Australia
Terho Lehtimäki
41Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland
42Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33014, Finland
Vilmundur Gudnason
12Icelandic Heart Association, Kopavogur 201, Iceland
85Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland
Alanna C Morrison
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
Alexandre C Pereira
14Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo 5403000, Brazil
86Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Myriam Fornage
13Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
15Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA
Bruce M Psaty
87Cardiovascular Health Research Unit, Departments of Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA 98101, USA
88Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, USA
Cornelia M van Duijn
17Department of Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
89Nuffield Department of Population Health, University of Oxford, Oxford, UK
Ching-Ti Liu
19Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
Tanika N Kelly
20Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112 USA
Michele K Evans
22Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Claude Bouchard
23Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Ervin R Fox
24Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39213, USA
Charles Kooperberg
90Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Xiaofeng Zhu
91Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH 44106, USA
Timo A Lakka
26Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland
66Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland
92Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio 70029, Finland
Tõnu Esko
27Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia
Kari E North
25Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC 27516, USA
Ian J Deary
30Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK
Harold Snieder
31Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, The Netherlands
Brenda WJH Penninx
69Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam 1081 BT, The Netherlands
James Gauderman
93Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, California, USA
Dabeeru C Rao
4Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA
Susan Redline
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA
94Division of Pulmonary Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
Diana van Heemst
3Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333ZA, The Netherlands
Posted May 31, 2020.
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Heming Wang, Raymond Noordam, Brian E Cade, Karen Schwander, Thomas W Winkler, Jiwon Lee, Yun Ju Sung, Amy R. Bentley, Alisa K Manning, Hugues Aschard, Tuomas O Kilpeläinen, Marjan Ilkov, Michael R Brown, Andrea R Horimoto, Melissa Richard, Traci M Bartz, Dina Vojinovic, Elise Lim, Jovia L Nierenberg, Yongmei Liu, Kumaraswamynaidu Chitrala, Tuomo Rankinen, Solomon K Musani, Nora Franceschini, Rainer Rauramaa, Maris Alver, Phyllis Zee, Sarah E Harris, Peter J van der Most, Ilja M Nolte, Patricia B Munroe, Nicholette D Palmer, Brigitte Kühnel, Stefan Weiss, Wanqing Wen, Kelly A Hall, Leo-Pekka Lyytikäinen, Jeff O’Connell, Gudny Eiriksdottir, Lenore J Launer, Paul S de Vries, Dan E Arking, Han Chen, Eric Boerwinkle, Jose E Krieger, Pamela J Schreiner, Stephen S Sidney, James M Shikany, Kenneth Rice, Yii-Der Ida Chen, Sina A Gharib, Joshua C Bis, Annemarie I Luik, M Arfan Ikram, André G Uitterlinden, Najaf Amin, Hanfei Xu, Daniel Levy, Jiang He, Kurt K Lohman, Alan B Zonderman, Treva K Rice, Mario Sims, Gregory Wilson, Tamar Sofer, Stephen S Rich, Walter Palmas, Jie Yao, Xiuqing Guo, Jerome I Rotter, Nienke R Biermasz, Dennis O Mook-Kanamori, Lisa W Martin, Ana Barac, Robert B Wallace, Daniel Gottlieb, Pirjo Komulainen, Sami Heikkinen, Reedik Mägi, Lili Milani, Andres Metspalu, John M Starr, Yuri Milaneschi, RJ Waken, Chuan Gao, Melanie Waldenberger, Annette Peters, Konstantin Strauch, Thomas Meitinger, Till Roenneberg, Uwe Völker, Marcus Dörr, Xiao-Ou Shu, Sutapa Mukherjee, David R Hillman, Mika Kähönen, Lynne E Wagenknecht, Christian Gieger, Hans J Grabe, Wei Zheng, Lyle J Palmer, Terho Lehtimäki, Vilmundur Gudnason, Alanna C Morrison, Alexandre C Pereira, Myriam Fornage, Bruce M Psaty, Cornelia M van Duijn, Ching-Ti Liu, Tanika N Kelly, Michele K Evans, Claude Bouchard, Ervin R Fox, Charles Kooperberg, Xiaofeng Zhu, Timo A Lakka, Tõnu Esko, Kari E North, Ian J Deary, Harold Snieder, Brenda WJH Penninx, James Gauderman, Dabeeru C Rao, Susan Redline, Diana van Heemst
bioRxiv 2020.05.29.123505; doi: https://doi.org/10.1101/2020.05.29.123505
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure
Heming Wang, Raymond Noordam, Brian E Cade, Karen Schwander, Thomas W Winkler, Jiwon Lee, Yun Ju Sung, Amy R. Bentley, Alisa K Manning, Hugues Aschard, Tuomas O Kilpeläinen, Marjan Ilkov, Michael R Brown, Andrea R Horimoto, Melissa Richard, Traci M Bartz, Dina Vojinovic, Elise Lim, Jovia L Nierenberg, Yongmei Liu, Kumaraswamynaidu Chitrala, Tuomo Rankinen, Solomon K Musani, Nora Franceschini, Rainer Rauramaa, Maris Alver, Phyllis Zee, Sarah E Harris, Peter J van der Most, Ilja M Nolte, Patricia B Munroe, Nicholette D Palmer, Brigitte Kühnel, Stefan Weiss, Wanqing Wen, Kelly A Hall, Leo-Pekka Lyytikäinen, Jeff O’Connell, Gudny Eiriksdottir, Lenore J Launer, Paul S de Vries, Dan E Arking, Han Chen, Eric Boerwinkle, Jose E Krieger, Pamela J Schreiner, Stephen S Sidney, James M Shikany, Kenneth Rice, Yii-Der Ida Chen, Sina A Gharib, Joshua C Bis, Annemarie I Luik, M Arfan Ikram, André G Uitterlinden, Najaf Amin, Hanfei Xu, Daniel Levy, Jiang He, Kurt K Lohman, Alan B Zonderman, Treva K Rice, Mario Sims, Gregory Wilson, Tamar Sofer, Stephen S Rich, Walter Palmas, Jie Yao, Xiuqing Guo, Jerome I Rotter, Nienke R Biermasz, Dennis O Mook-Kanamori, Lisa W Martin, Ana Barac, Robert B Wallace, Daniel Gottlieb, Pirjo Komulainen, Sami Heikkinen, Reedik Mägi, Lili Milani, Andres Metspalu, John M Starr, Yuri Milaneschi, RJ Waken, Chuan Gao, Melanie Waldenberger, Annette Peters, Konstantin Strauch, Thomas Meitinger, Till Roenneberg, Uwe Völker, Marcus Dörr, Xiao-Ou Shu, Sutapa Mukherjee, David R Hillman, Mika Kähönen, Lynne E Wagenknecht, Christian Gieger, Hans J Grabe, Wei Zheng, Lyle J Palmer, Terho Lehtimäki, Vilmundur Gudnason, Alanna C Morrison, Alexandre C Pereira, Myriam Fornage, Bruce M Psaty, Cornelia M van Duijn, Ching-Ti Liu, Tanika N Kelly, Michele K Evans, Claude Bouchard, Ervin R Fox, Charles Kooperberg, Xiaofeng Zhu, Timo A Lakka, Tõnu Esko, Kari E North, Ian J Deary, Harold Snieder, Brenda WJH Penninx, James Gauderman, Dabeeru C Rao, Susan Redline, Diana van Heemst
bioRxiv 2020.05.29.123505; doi: https://doi.org/10.1101/2020.05.29.123505
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