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Structural basis for stereospecific inhibition of ASCT2 from rational design

View ORCID ProfileRachel-Ann A. Garibsingh, View ORCID ProfileElias Ndaru, View ORCID ProfileAlisa A. Garaeva, View ORCID ProfileMassimiliano Bonomi, View ORCID ProfileDirk J. Slotboom, View ORCID ProfileCristina Paulino, View ORCID ProfileChristof Grewer, View ORCID ProfileAvner Schlessinger
doi: https://doi.org/10.1101/2020.05.29.124305
Rachel-Ann A. Garibsingh
1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029
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  • ORCID record for Rachel-Ann A. Garibsingh
Elias Ndaru
2Department of Chemistry, Binghamton University, Binghamton, NY
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Alisa A. Garaeva
3Membrane Enzymology, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Groningen, the Netherlands
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  • ORCID record for Alisa A. Garaeva
Massimiliano Bonomi
4Structural Bioinformatics Unit, Department of Structural Biology and Chemistry; CNRS UMR 3528; C3BI, CNRS USR 3756; Institut Pasteur, Paris, France
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Dirk J. Slotboom
3Membrane Enzymology, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Groningen, the Netherlands
6University of Groningen, Zernike Institute for Advanced Materials, Groningen, The Netherlands
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Cristina Paulino
5Structural Biology, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, Groningen, The Netherlands
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Christof Grewer
2Department of Chemistry, Binghamton University, Binghamton, NY
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Avner Schlessinger
1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029
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  • For correspondence: avner.schlessinger@mssm.edu
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Posted May 31, 2020.
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Structural basis for stereospecific inhibition of ASCT2 from rational design
Rachel-Ann A. Garibsingh, Elias Ndaru, Alisa A. Garaeva, Massimiliano Bonomi, Dirk J. Slotboom, Cristina Paulino, Christof Grewer, Avner Schlessinger
bioRxiv 2020.05.29.124305; doi: https://doi.org/10.1101/2020.05.29.124305
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Structural basis for stereospecific inhibition of ASCT2 from rational design
Rachel-Ann A. Garibsingh, Elias Ndaru, Alisa A. Garaeva, Massimiliano Bonomi, Dirk J. Slotboom, Cristina Paulino, Christof Grewer, Avner Schlessinger
bioRxiv 2020.05.29.124305; doi: https://doi.org/10.1101/2020.05.29.124305

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