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Sofosbuvir protects human brain organoids against SARS-CoV-2
View ORCID ProfilePinar Mesci, Angela Macia, Aurian Saleh, Laura Martin-Sancho, View ORCID ProfileXin Yin, Cedric Snethlage, Simoni Avansini, Sumit K. Chanda, View ORCID ProfileAlysson Muotri
doi: https://doi.org/10.1101/2020.05.30.125856
Pinar Mesci
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
Angela Macia
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
Aurian Saleh
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
Laura Martin-Sancho
2Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA
Xin Yin
2Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA
Cedric Snethlage
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
Simoni Avansini
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
Sumit K. Chanda
2Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA
Alysson Muotri
1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children’s Hospital San Diego, Department of Cellular & Molecular Medicine, La Jolla, CA 92037
3University of California San Diego, Kavli Institute for Brain and Mind, Center for Academic Research and Training in Anthropogeny (CARTA), La Jolla, CA 92093, USA

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Posted May 31, 2020.
Sofosbuvir protects human brain organoids against SARS-CoV-2
Pinar Mesci, Angela Macia, Aurian Saleh, Laura Martin-Sancho, Xin Yin, Cedric Snethlage, Simoni Avansini, Sumit K. Chanda, Alysson Muotri
bioRxiv 2020.05.30.125856; doi: https://doi.org/10.1101/2020.05.30.125856
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