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Codon arrangement modulates MHC-I peptides presentation

Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault
doi: https://doi.org/10.1101/2020.06.03.078824
Tariq Daouda
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
2Department of Biochemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Maude Dumont-Lagacé
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Albert Feghaly
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Yahya Benslimane
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Rébecca Panes
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
4Department of Microbiology, Infectiology and Immunology; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Mathieu Courcelles
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
5Department of Chemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Mohamed Benhammadi
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Lea Harrington
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Pierre Thibault
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
5Department of Chemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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François Major
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
6Department of Informatics and Operational Research; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Yoshua Bengio
6Department of Informatics and Operational Research; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Étienne Gagnon
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
4Department of Microbiology, Infectiology and Immunology; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Sébastien Lemieux
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
2Department of Biochemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
6Department of Informatics and Operational Research; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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Claude Perreault
1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
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  • For correspondence: claude.perreault@umontreal.ca
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Article Information

doi 
https://doi.org/10.1101/2020.06.03.078824
History 
  • June 4, 2020.

Article Versions

  • You are currently viewing Version 1 of this article (June 4, 2020 - 16:03).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Tariq Daouda1,2,7,
  2. Maude Dumont-Lagacé1,3,7,
  3. Albert Feghaly1,
  4. Yahya Benslimane1,3,
  5. Rébecca Panes1,4,
  6. Mathieu Courcelles1,5,
  7. Mohamed Benhammadi1,3,
  8. Lea Harrington1,3,
  9. Pierre Thibault1,5,
  10. François Major1,6,
  11. Yoshua Bengio6,
  12. Étienne Gagnon1,4,
  13. Sébastien Lemieux1,2,6 and
  14. Claude Perreault1,3,*
  1. 1Institute for Research in Immunology and Cancer; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  2. 2Department of Biochemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  3. 3Department of Medicine; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  4. 4Department of Microbiology, Infectiology and Immunology; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  5. 5Department of Chemistry; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  6. 6Department of Informatics and Operational Research; Université de Montréal; Montréal, Québec H3C 3J7, Canada
  1. ↵*Corresponding author: Claude Perreault (claude.perreault{at}umontreal.ca).
  1. ↵7 These authors contributed equally.

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Posted June 04, 2020.
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Codon arrangement modulates MHC-I peptides presentation
Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault
bioRxiv 2020.06.03.078824; doi: https://doi.org/10.1101/2020.06.03.078824
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Codon arrangement modulates MHC-I peptides presentation
Tariq Daouda, Maude Dumont-Lagacé, Albert Feghaly, Yahya Benslimane, Rébecca Panes, Mathieu Courcelles, Mohamed Benhammadi, Lea Harrington, Pierre Thibault, François Major, Yoshua Bengio, Étienne Gagnon, Sébastien Lemieux, Claude Perreault
bioRxiv 2020.06.03.078824; doi: https://doi.org/10.1101/2020.06.03.078824

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