Purification of age-distinct insulin secretory granules through antigen restriction using the CLIP-tag

Martin Neukam; Katharina Ganß; Jovana Vasiljević; Johannes Broichhagen; Kai Johnsson; Thomas Kurth; Michele Solimena

doi:10.1101/2020.06.03.103770

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Purification of age-distinct insulin secretory granules through antigen restriction using the CLIP-tag

View ORCID ProfileMartin Neukam, Katharina Ganß, View ORCID ProfileJovana Vasiljević, View ORCID ProfileJohannes Broichhagen, View ORCID ProfileKai Johnsson, View ORCID ProfileThomas Kurth, View ORCID ProfileMichele Solimena

doi: https://doi.org/10.1101/2020.06.03.103770

Martin Neukam

1Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Katharina Ganß

1Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Jovana Vasiljević

1Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

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Johannes Broichhagen

4Max-Planck-Institute for Medical Research, Department of Chemical Biology, Heidelberg, Germany

5Forschungsinstitut für Molekulare Pharmakologie, Department of Chemical Biology, Berlin, Germany

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Kai Johnsson

4Max-Planck-Institute for Medical Research, Department of Chemical Biology, Heidelberg, Germany

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Thomas Kurth

6TU Dresden, Center for Molecular and Cellular Bioengineering (CMCB), Technology Platform, Dresden, Germany

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Michele Solimena

1Molecular Diabetology, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany

2Paul Langerhans Institute Dresden (PLID) of the Helmholtz Center Munich at the University Hospital Carl Gustav Carus and Faculty of Medicine of the TU Dresden, Dresden, Germany

3German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany

7Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany

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For correspondence: Michele.Solimena@uniklinikum-dresden.de

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Purification of age-distinct insulin secretory granules through antigen restriction using the CLIP-tag

Martin Neukam, Katharina Ganß, Jovana Vasiljević, Johannes Broichhagen, Kai Johnsson, Thomas Kurth, Michele Solimena

bioRxiv 2020.06.03.103770; doi: https://doi.org/10.1101/2020.06.03.103770

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Purification of age-distinct insulin secretory granules through antigen restriction using the CLIP-tag

Martin Neukam, Katharina Ganß, Jovana Vasiljević, Johannes Broichhagen, Kai Johnsson, Thomas Kurth, Michele Solimena

bioRxiv 2020.06.03.103770; doi: https://doi.org/10.1101/2020.06.03.103770

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