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A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W. Sutherland, Jeffrey C. Hertz, Jean-Marc Bonneville, Victor Arnaud, Camille Noûs, Bénédicte Fustec, Sébastien Boyer, Sébastien Marcombe, Jean-Philippe David
doi: https://doi.org/10.1101/2020.06.08.139741
Julien Cattel
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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  • For correspondence: juliencattel@gmail.com
Chloé Haberkorn
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Fréderic Laporte
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Thierry Gaude
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Tristan Cumer
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Julien Renaud
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Ian W. Sutherland
2United States Navy Entomology. Center of Excellence, NAS Jacksonville, Florida, United States of America
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Jeffrey C. Hertz
3US Naval Medical Research Unit No. 2, Singapore
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Jean-Marc Bonneville
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Victor Arnaud
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Camille Noûs
4Laboratoire Cogitamus, 1 ¾ rue Descartes, 75005 Paris, France
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Bénédicte Fustec
5Department of Microbiology, Khon Kaen University, Khon Kaen, Thailand
6Institut de Recherche pour le Développement, UMR IRD 224-CNRS 5290-Université Montpellier. 911, avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, FRANCE
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Sébastien Boyer
7Medical and Veterinary Entomology, Institut Pasteur du Cambodge, P.O Box. 983 Phnom Penh, Cambodia
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Sébastien Marcombe
8Medical Entomology and Vector-Borne Disease Laboratory, Institut Pasteur du Laos, Vientiane, Laos
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Jean-Philippe David
1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France
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Posted November 04, 2020.
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A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W. Sutherland, Jeffrey C. Hertz, Jean-Marc Bonneville, Victor Arnaud, Camille Noûs, Bénédicte Fustec, Sébastien Boyer, Sébastien Marcombe, Jean-Philippe David
bioRxiv 2020.06.08.139741; doi: https://doi.org/10.1101/2020.06.08.139741
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A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W. Sutherland, Jeffrey C. Hertz, Jean-Marc Bonneville, Victor Arnaud, Camille Noûs, Bénédicte Fustec, Sébastien Boyer, Sébastien Marcombe, Jean-Philippe David
bioRxiv 2020.06.08.139741; doi: https://doi.org/10.1101/2020.06.08.139741

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