A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

Julien Cattel; Chloé Haberkorn; Fréderic Laporte; Thierry Gaude; Tristan Cumer; Julien Renaud; Ian W. Sutherland; Jeffrey C. Hertz; Jean-Marc Bonneville; Victor Arnaud; Camille Noûs; Bénédicte Fustec; Sébastien Boyer; Sébastien Marcombe; Jean-Philippe David

doi:10.1101/2020.06.08.139741

New Results

A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

Julien Cattel, Chloé Haberkorn, Fréderic Laporte, Thierry Gaude, Tristan Cumer, Julien Renaud, Ian W. Sutherland, Jeffrey C. Hertz, Jean-Marc Bonneville, Victor Arnaud, Camille Noûs, Bénédicte Fustec, Sébastien Boyer, Sébastien Marcombe, Jean-Philippe David

doi: https://doi.org/10.1101/2020.06.08.139741

Julien Cattel

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: juliencattel@gmail.com

Chloé Haberkorn

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Fréderic Laporte

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Thierry Gaude

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Tristan Cumer

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Julien Renaud

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ian W. Sutherland

2United States Navy Entomology. Center of Excellence, NAS Jacksonville, Florida, United States of America

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jeffrey C. Hertz

3US Naval Medical Research Unit No. 2, Singapore

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jean-Marc Bonneville

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Victor Arnaud

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Camille Noûs

4Laboratoire Cogitamus, 1 ¾ rue Descartes, 75005 Paris, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Bénédicte Fustec

5Department of Microbiology, Khon Kaen University, Khon Kaen, Thailand

6Institut de Recherche pour le Développement, UMR IRD 224-CNRS 5290-Université Montpellier. 911, avenue Agropolis, BP 64501, 34394 Montpellier Cedex 5, FRANCE

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sébastien Boyer

7Medical and Veterinary Entomology, Institut Pasteur du Cambodge, P.O Box. 983 Phnom Penh, Cambodia

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sébastien Marcombe

8Medical Entomology and Vector-Borne Disease Laboratory, Institut Pasteur du Laos, Vientiane, Laos

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jean-Philippe David

1Laboratoire d’Ecologie Alpine (LECA), UMR 5553 CNRS – Université Grenoble-Alpes, 2233 rue de la piscine, Grenoble, France

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Abstract
Full Text
Info/History
Metrics
Data/Code
Preview PDF

https://zenodo.org/record/4243761#.X6JBUWgzZPZ

View the discussion thread.

PreviousNext

Posted November 04, 2020.

Download PDF

Data/Code

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

bioRxiv 2020.06.08.139741; doi: https://doi.org/10.1101/2020.06.08.139741

Share This Article:

Citation Tools

A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection

bioRxiv 2020.06.08.139741; doi: https://doi.org/10.1101/2020.06.08.139741

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Evolutionary Biology

Subject Areas

All Articles

Animal Behavior and Cognition (4397)
Biochemistry (9624)
Bioengineering (7120)
Bioinformatics (24937)
Biophysics (12665)
Cancer Biology (9991)
Cell Biology (14395)
Clinical Trials (138)
Developmental Biology (7988)
Ecology (12146)
Epidemiology (2067)
Evolutionary Biology (16022)
Genetics (10950)
Genomics (14778)
Immunology (9899)
Microbiology (23732)
Molecular Biology (9503)
Neuroscience (51045)
Paleontology (370)
Pathology (1544)
Pharmacology and Toxicology (2692)
Physiology (4037)
Plant Biology (8693)
Scientific Communication and Education (1512)
Synthetic Biology (2404)
Systems Biology (6456)
Zoology (1349)