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Synaptic accumulation of FUS triggers age-dependent misregulation of inhibitory synapses in ALS-FUS mice

Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
doi: https://doi.org/10.1101/2020.06.10.136010
Sonu Sahadevan
1Department of Quantitative Biomedicine, University of Zurich
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Katharina M. Hembach
1Department of Quantitative Biomedicine, University of Zurich
2Department of Molecular Life Sciences and SIB Swiss Institute of Bioinformatics, University of Zurich
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Elena Tantardini
1Department of Quantitative Biomedicine, University of Zurich
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Manuela Pérez-Berlanga
1Department of Quantitative Biomedicine, University of Zurich
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Marian Hruska-Plochan
1Department of Quantitative Biomedicine, University of Zurich
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Julien Weber
1Department of Quantitative Biomedicine, University of Zurich
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Petra Schwarz
3Institute of Neuropathology, University Hospital Zurich
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Luc Dupuis
4Inserm, University of Strasbourg
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Mark D. Robinson
2Department of Molecular Life Sciences and SIB Swiss Institute of Bioinformatics, University of Zurich
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Pierre De Rossi
1Department of Quantitative Biomedicine, University of Zurich
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Magdalini Polymenidou
1Department of Quantitative Biomedicine, University of Zurich
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  • For correspondence: magdalini.polymenidou@uzh.ch
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Article Information

doi 
https://doi.org/10.1101/2020.06.10.136010
History 
  • June 10, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Sonu Sahadevan1,*,
  2. Katharina M. Hembach1,2,*,
  3. Elena Tantardini1,
  4. Manuela Pérez-Berlanga1,
  5. Marian Hruska-Plochan1,
  6. Julien Weber1,
  7. Petra Schwarz3,
  8. Luc Dupuis4,
  9. Mark D. Robinson2,
  10. Pierre De Rossi1 and
  11. Magdalini Polymenidou1,#
  1. 1Department of Quantitative Biomedicine, University of Zurich
  2. 2Department of Molecular Life Sciences and SIB Swiss Institute of Bioinformatics, University of Zurich
  3. 3Institute of Neuropathology, University Hospital Zurich
  4. 4Inserm, University of Strasbourg
  1. ↵#Author for correspondence: magdalini.polymenidou{at}uzh.ch
  1. ↵* These authors contributed equally to this work

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Posted June 10, 2020.
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Synaptic accumulation of FUS triggers age-dependent misregulation of inhibitory synapses in ALS-FUS mice
Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
bioRxiv 2020.06.10.136010; doi: https://doi.org/10.1101/2020.06.10.136010
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Synaptic accumulation of FUS triggers age-dependent misregulation of inhibitory synapses in ALS-FUS mice
Sonu Sahadevan, Katharina M. Hembach, Elena Tantardini, Manuela Pérez-Berlanga, Marian Hruska-Plochan, Julien Weber, Petra Schwarz, Luc Dupuis, Mark D. Robinson, Pierre De Rossi, Magdalini Polymenidou
bioRxiv 2020.06.10.136010; doi: https://doi.org/10.1101/2020.06.10.136010

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