Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi:β-arrestin complexes

Kevin Zheng; Jeffrey S. Smith; Anmol Warman; Issac Choi; Jaimee N. Gundry; Thomas F. Pack; Asuka Inoue; Marc G. Caron; Sudarshan Rajagopal

doi:10.1101/2020.06.11.146605

New Results

Biased agonists of the chemokine receptor CXCR3 differentially drive formation of G_αi:β-arrestin complexes

View ORCID ProfileKevin Zheng, View ORCID ProfileJeffrey S. Smith, View ORCID ProfileAnmol Warman, Issac Choi, Jaimee N. Gundry, View ORCID ProfileThomas F. Pack, Asuka Inoue, Marc G. Caron, View ORCID ProfileSudarshan Rajagopal

doi: https://doi.org/10.1101/2020.06.11.146605

Kevin Zheng

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Kevin Zheng

Jeffrey S. Smith

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

2Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Jeffrey S. Smith

Anmol Warman

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Anmol Warman

Issac Choi

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jaimee N. Gundry

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Thomas F. Pack

3Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA

4Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Thomas F. Pack

Asuka Inoue

5Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Marc G. Caron

3Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA

6Department of Pharmaceutical Sciences, Tohoku University, Japan

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sudarshan Rajagopal

1Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA

2Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Sudarshan Rajagopal
For correspondence: sudarshan.rajagopal@duke.edu

Abstract
Full Text
Info/History
Metrics
Supplementary material
Preview PDF

Supplementals[supplements/146605_file03.pdf]

View the discussion thread.

PreviousNext

Posted June 12, 2020.

Download PDF

Supplementary Material

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi:β-arrestin complexes

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Biased agonists of the chemokine receptor CXCR3 differentially drive formation of G_αi:β-arrestin complexes

Kevin Zheng, Jeffrey S. Smith, Anmol Warman, Issac Choi, Jaimee N. Gundry, Thomas F. Pack, Asuka Inoue, Marc G. Caron, Sudarshan Rajagopal

bioRxiv 2020.06.11.146605; doi: https://doi.org/10.1101/2020.06.11.146605

Share This Article:

Citation Tools

Biased agonists of the chemokine receptor CXCR3 differentially drive formation of G_αi:β-arrestin complexes

Kevin Zheng, Jeffrey S. Smith, Anmol Warman, Issac Choi, Jaimee N. Gundry, Thomas F. Pack, Asuka Inoue, Marc G. Caron, Sudarshan Rajagopal

bioRxiv 2020.06.11.146605; doi: https://doi.org/10.1101/2020.06.11.146605

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Biochemistry

Subject Areas

All Articles

Animal Behavior and Cognition (4840)
Biochemistry (10766)
Bioengineering (8026)
Bioinformatics (27215)
Biophysics (13947)
Cancer Biology (11095)
Cell Biology (16016)
Clinical Trials (138)
Developmental Biology (8764)
Ecology (13254)
Epidemiology (2067)
Evolutionary Biology (17332)
Genetics (11669)
Genomics (15890)
Immunology (11004)
Microbiology (26023)
Molecular Biology (10620)
Neuroscience (56406)
Paleontology (417)
Pathology (1729)
Pharmacology and Toxicology (2999)
Physiology (4534)
Plant Biology (9599)
Scientific Communication and Education (1610)
Synthetic Biology (2677)
Systems Biology (6963)
Zoology (1508)