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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction

Mukhtar Sadykov, Tobias Mourier, Qingtian Guan, View ORCID ProfileArnab Pain
doi: https://doi.org/10.1101/2020.06.19.161687
Mukhtar Sadykov
1King Abdullah University of Science and Technology (KAUST), Pathogen Genomics Laboratory, Biological and Environmental Science and Engineering (BESE), Thuwal-Jeddah, 23955-6900, Saudi Arabia
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Tobias Mourier
1King Abdullah University of Science and Technology (KAUST), Pathogen Genomics Laboratory, Biological and Environmental Science and Engineering (BESE), Thuwal-Jeddah, 23955-6900, Saudi Arabia
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Qingtian Guan
1King Abdullah University of Science and Technology (KAUST), Pathogen Genomics Laboratory, Biological and Environmental Science and Engineering (BESE), Thuwal-Jeddah, 23955-6900, Saudi Arabia
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Arnab Pain
1King Abdullah University of Science and Technology (KAUST), Pathogen Genomics Laboratory, Biological and Environmental Science and Engineering (BESE), Thuwal-Jeddah, 23955-6900, Saudi Arabia
2Research Center for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE); Hokkaido University, N20 W10 Kita-ku, Sapporo, 001-0020 Japan
3Nuffield Division of Clinical Laboratory Sciences (NDCLS), University of Oxford, Headington, Oxford, OX3 9DU, United Kingdom
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  • ORCID record for Arnab Pain
  • For correspondence: arnab.pain@kaust.edu.sa
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Article Information

doi 
https://doi.org/10.1101/2020.06.19.161687
History 
  • January 5, 2021.

Article Versions

  • Version 1 (June 19, 2020 - 19:49).
  • Version 2 (June 22, 2020 - 15:42).
  • Version 3 (August 7, 2020 - 10:53).
  • You are viewing Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Mukhtar Sadykov1,*,
  2. Tobias Mourier1,*,
  3. Qingtian Guan1 and
  4. Arnab Pain1,2,3,**
  1. 1King Abdullah University of Science and Technology (KAUST), Pathogen Genomics Laboratory, Biological and Environmental Science and Engineering (BESE), Thuwal-Jeddah, 23955-6900, Saudi Arabia
  2. 2Research Center for Zoonosis Control, Global Institution for Collaborative Research and Education (GI-CoRE); Hokkaido University, N20 W10 Kita-ku, Sapporo, 001-0020 Japan
  3. 3Nuffield Division of Clinical Laboratory Sciences (NDCLS), University of Oxford, Headington, Oxford, OX3 9DU, United Kingdom
  1. ↵**Correspondence:
    Arnab Pain Email: arnab.pain{at}kaust.edu.sa. King Abdullah University of Science and Technology, Jeddah, Saudi Arabia. Phone: (+966) 54 470 0687
  1. ↵* These authors contributed equally

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Posted January 05, 2021.
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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction
Mukhtar Sadykov, Tobias Mourier, Qingtian Guan, Arnab Pain
bioRxiv 2020.06.19.161687; doi: https://doi.org/10.1101/2020.06.19.161687
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Short sequence motif dynamics in the SARS-CoV-2 genome suggest a role for cytosine deamination in CpG reduction
Mukhtar Sadykov, Tobias Mourier, Qingtian Guan, Arnab Pain
bioRxiv 2020.06.19.161687; doi: https://doi.org/10.1101/2020.06.19.161687

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