Phage proteins block and trigger retron toxin/antitoxin systems

Jacob Bobonis; Karin Mitosch; André Mateus; George Kritikos; Johanna R. Elfenbein; Mikhail M. Savitski; Helene Andrews-Polymenis; Athanasios Typas

doi:10.1101/2020.06.22.160242

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Phage proteins block and trigger retron toxin/antitoxin systems

View ORCID ProfileJacob Bobonis, View ORCID ProfileKarin Mitosch, View ORCID ProfileAndré Mateus, View ORCID ProfileGeorge Kritikos, View ORCID ProfileJohanna R. Elfenbein, View ORCID ProfileMikhail M. Savitski, View ORCID ProfileHelene Andrews-Polymenis, View ORCID ProfileAthanasios Typas

doi: https://doi.org/10.1101/2020.06.22.160242

Jacob Bobonis

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

2Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences

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Karin Mitosch

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

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André Mateus

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

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George Kritikos

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

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Johanna R. Elfenbein

3University of Wisconsin-Madison, Department of Pathobiological Sciences, Madison, WI, USA

4North Carolina State University, Department of Clinical Sciences, North Carolina, USA

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Mikhail M. Savitski

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

5European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany

6European Molecular Biology Laboratory, Proteomics Core Facility, Heidelberg, Germany

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Helene Andrews-Polymenis

7Texas A&M University, Department of Microbial Pathogenesis and Immunology, Texas, USA

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Athanasios Typas

1European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany

5European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany

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For correspondence: typas@embl.de

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Phage proteins block and trigger retron toxin/antitoxin systems

Jacob Bobonis, Karin Mitosch, André Mateus, George Kritikos, Johanna R. Elfenbein, Mikhail M. Savitski, Helene Andrews-Polymenis, Athanasios Typas

bioRxiv 2020.06.22.160242; doi: https://doi.org/10.1101/2020.06.22.160242

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Phage proteins block and trigger retron toxin/antitoxin systems

Jacob Bobonis, Karin Mitosch, André Mateus, George Kritikos, Johanna R. Elfenbein, Mikhail M. Savitski, Helene Andrews-Polymenis, Athanasios Typas

bioRxiv 2020.06.22.160242; doi: https://doi.org/10.1101/2020.06.22.160242

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