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RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
View ORCID ProfileAyshwarya Subramanian, View ORCID ProfileKatherine A Vernon, Michal Slyper, Julia Waldman, View ORCID ProfileMalte D Luecken, View ORCID ProfileKirk Gosik, Dan Dubinsky, Michael S Cuoco, View ORCID ProfileKeith Keller, Jason Purnell, Lan Nguyen, View ORCID ProfileDanielle Dionne, Orit Rozenblatt-Rosen, Astrid Weins, Human Cell Atlas Lung Biological Network, View ORCID ProfileAviv Regev, View ORCID ProfileAnna Greka
doi: https://doi.org/10.1101/2020.06.23.167098
Ayshwarya Subramanian
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
3Kidney Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Katherine A Vernon
2Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
3Kidney Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Michal Slyper
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Julia Waldman
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Malte D Luecken
4Institute of Computational Biology, Helmholtz Zentrum München, Munich, Germany
Kirk Gosik
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Dan Dubinsky
5Genomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Michael S Cuoco
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Keith Keller
6Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
Jason Purnell
5Genomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Lan Nguyen
5Genomics Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Danielle Dionne
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Orit Rozenblatt-Rosen
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Astrid Weins
6Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
Aviv Regev
1Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Anna Greka
2Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
3Kidney Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Article usage
Posted July 01, 2020.
RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Ayshwarya Subramanian, Katherine A Vernon, Michal Slyper, Julia Waldman, Malte D Luecken, Kirk Gosik, Dan Dubinsky, Michael S Cuoco, Keith Keller, Jason Purnell, Lan Nguyen, Danielle Dionne, Orit Rozenblatt-Rosen, Astrid Weins, Human Cell Atlas Lung Biological Network, Aviv Regev, Anna Greka
bioRxiv 2020.06.23.167098; doi: https://doi.org/10.1101/2020.06.23.167098
RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Ayshwarya Subramanian, Katherine A Vernon, Michal Slyper, Julia Waldman, Malte D Luecken, Kirk Gosik, Dan Dubinsky, Michael S Cuoco, Keith Keller, Jason Purnell, Lan Nguyen, Danielle Dionne, Orit Rozenblatt-Rosen, Astrid Weins, Human Cell Atlas Lung Biological Network, Aviv Regev, Anna Greka
bioRxiv 2020.06.23.167098; doi: https://doi.org/10.1101/2020.06.23.167098
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