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Reduced nuclear lamin A/C enhances cancer cell squeezing through rigid barriers, does not facilitate endothelial crossing, and impairs experimental metastasis
View ORCID ProfileFrancesco Roncato, View ORCID ProfileOfer Regev, View ORCID ProfileSara W. Feigelson, Sandeep Kumar Yadav, Lukasz Kaczmarczyk, Nehora Levi, View ORCID ProfileDiana Drago-Garcia, View ORCID ProfileSamuel Ovadia, View ORCID ProfileMarina Kizner, View ORCID ProfileYoseph Addadi, View ORCID ProfileJoão Cruz Sabino, Yossi Ovadya, View ORCID ProfileSérgio Fernandes de Almeida, View ORCID ProfileEster Feldmesser, View ORCID ProfileGabi Gerlitz, View ORCID ProfileRonen Alon
doi: https://doi.org/10.1101/2020.06.23.167130
Francesco Roncato
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Ofer Regev
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Sara W. Feigelson
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Sandeep Kumar Yadav
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Lukasz Kaczmarczyk
2Department of Molecular Biology, Ariel University, Kiryat Hamada, Ariel, 40700, Israel
Nehora Levi
2Department of Molecular Biology, Ariel University, Kiryat Hamada, Ariel, 40700, Israel
Diana Drago-Garcia
3Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel
Samuel Ovadia
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Marina Kizner
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Yoseph Addadi
4Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot, 76100, Israel
João Cruz Sabino
5Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, 1649-028, Portugal
Yossi Ovadya
6Department of Molecular Cell Biology, Weizmann Institute of Science, 76100 Rehovot, Israel
Sérgio Fernandes de Almeida
5Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, 1649-028, Portugal
Ester Feldmesser
3Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel
Gabi Gerlitz
2Department of Molecular Biology, Ariel University, Kiryat Hamada, Ariel, 40700, Israel
Ronen Alon
1Department of Immunology, Weizmann Institute of Science, Rehovot, 76100, Israel
Posted June 24, 2020.
Reduced nuclear lamin A/C enhances cancer cell squeezing through rigid barriers, does not facilitate endothelial crossing, and impairs experimental metastasis
Francesco Roncato, Ofer Regev, Sara W. Feigelson, Sandeep Kumar Yadav, Lukasz Kaczmarczyk, Nehora Levi, Diana Drago-Garcia, Samuel Ovadia, Marina Kizner, Yoseph Addadi, João Cruz Sabino, Yossi Ovadya, Sérgio Fernandes de Almeida, Ester Feldmesser, Gabi Gerlitz, Ronen Alon
bioRxiv 2020.06.23.167130; doi: https://doi.org/10.1101/2020.06.23.167130
Reduced nuclear lamin A/C enhances cancer cell squeezing through rigid barriers, does not facilitate endothelial crossing, and impairs experimental metastasis
Francesco Roncato, Ofer Regev, Sara W. Feigelson, Sandeep Kumar Yadav, Lukasz Kaczmarczyk, Nehora Levi, Diana Drago-Garcia, Samuel Ovadia, Marina Kizner, Yoseph Addadi, João Cruz Sabino, Yossi Ovadya, Sérgio Fernandes de Almeida, Ester Feldmesser, Gabi Gerlitz, Ronen Alon
bioRxiv 2020.06.23.167130; doi: https://doi.org/10.1101/2020.06.23.167130
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