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Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, View ORCID ProfileFranck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David Jacobson, Roland Stein
doi: https://doi.org/10.1101/2020.06.29.177527
Emily M. Walker
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Jeeyeon Cha
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
2Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, VUMC, Nashville, TN, USA
Xin Tong
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Min Guo
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Jin-Hua Liu
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Sophia Yu
2Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, VUMC, Nashville, TN, USA
Donato Iacovazzo
3Centre for Endocrinology, Barts and The London School of Medicine, Queen Mary University of London, EC1M 6BQ London, United Kingdom
Franck Mauvais-Jarvis
4Section of Endocrinology and Metabolism, Department of Medicine, Tulane University Health Sciences Center, New Orleans, LA, USA
Sarah E. Flanagan
5Institute of Biomedical and Clinical Science, University of Exeter Medical School, EX2 5DW Exeter, United Kingdom
Márta Korbonits
3Centre for Endocrinology, Barts and The London School of Medicine, Queen Mary University of London, EC1M 6BQ London, United Kingdom
John Stafford
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
2Division of Diabetes, Endocrinology, and Metabolism, Department of Medicine, VUMC, Nashville, TN, USA
6Tennessee Valley Healthcare System, Veterans Affairs, Nashville, TN, USA
David Jacobson
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Roland Stein
1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA
Posted January 06, 2021.
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David Jacobson, Roland Stein
bioRxiv 2020.06.29.177527; doi: https://doi.org/10.1101/2020.06.29.177527
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David Jacobson, Roland Stein
bioRxiv 2020.06.29.177527; doi: https://doi.org/10.1101/2020.06.29.177527
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