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Sequential MAVS- and MyD88/TRIF-signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes

Luca Ghita, Veronika Breitkopf, Felix Mulenge, Andreas Pavlou, Olivia Luise Gern, Verónica Durán, Chittappen Kandiyil Prajeeth, Moritz Kohls, Klaus Jung, Martin Stangel, Imke Steffen, Ulrich Kalinke
doi: https://doi.org/10.1101/2020.06.30.177485
Luca Ghita
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
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Veronika Breitkopf
2Institute of Physiological Chemistry and Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany
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Felix Mulenge
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
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Andreas Pavlou
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
3Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany
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Olivia Luise Gern
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
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Verónica Durán
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
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Chittappen Kandiyil Prajeeth
3Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany
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Moritz Kohls
4Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, 30559 Hanover, Germany
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Klaus Jung
4Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover, 30559 Hanover, Germany
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Martin Stangel
3Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany
5Cluster of Excellence - Resolving Infection Susceptibility (RESIST, EXC 2155), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany
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Imke Steffen
2Institute of Physiological Chemistry and Research Center for Emerging Infections and Zoonoses (RIZ), University of Veterinary Medicine Hannover, Foundation, 30559 Hannover, Germany
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  • For correspondence: imke.steffen@tiho-hannover.de ulrich.kalinke@twincore.de
Ulrich Kalinke
1Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, 30625 Hannover, Germany
5Cluster of Excellence - Resolving Infection Susceptibility (RESIST, EXC 2155), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany
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  • For correspondence: imke.steffen@tiho-hannover.de ulrich.kalinke@twincore.de
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Posted July 02, 2020.
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Sequential MAVS- and MyD88/TRIF-signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes
Luca Ghita, Veronika Breitkopf, Felix Mulenge, Andreas Pavlou, Olivia Luise Gern, Verónica Durán, Chittappen Kandiyil Prajeeth, Moritz Kohls, Klaus Jung, Martin Stangel, Imke Steffen, Ulrich Kalinke
bioRxiv 2020.06.30.177485; doi: https://doi.org/10.1101/2020.06.30.177485
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Sequential MAVS- and MyD88/TRIF-signaling triggers anti-viral responses of tick-borne encephalitis virus-infected murine astrocytes
Luca Ghita, Veronika Breitkopf, Felix Mulenge, Andreas Pavlou, Olivia Luise Gern, Verónica Durán, Chittappen Kandiyil Prajeeth, Moritz Kohls, Klaus Jung, Martin Stangel, Imke Steffen, Ulrich Kalinke
bioRxiv 2020.06.30.177485; doi: https://doi.org/10.1101/2020.06.30.177485

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