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Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Douglas Ferreira Sales-Medina, Ludmila Rodrigues Pinto Ferreira, Lavínia M. D. Romera, Karolina Ribeiro Gonçalves, Rafael V. C. Guido, Gilles Courtemanche, Marcos S. Buckeridge, Édison L. Durigon, Carolina B. Moraes, Lucio H. Freitas-Junior
doi: https://doi.org/10.1101/2020.07.09.196337
Douglas Ferreira Sales-Medina
1Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo-SP 05508-900, Brazil
Ludmila Rodrigues Pinto Ferreira
2RNA Systems Biology Laboratory (RSBL), Post-Graduate Program in Cell Biology, Institute of Biological Sciences, Federal University of Minas Gerais & INCT-Vacinas, Av. Antônio Carlos, 6627, Belo Horizonte-MG 31270910, Brazil
Lavínia M. D. Romera
1Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo-SP 05508-900, Brazil
Karolina Ribeiro Gonçalves
1Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo-SP 05508-900, Brazil
Rafael V. C. Guido
3São Carlos Institute of Physics, University of Sao Paulo, Avenida João Dagnone, 1100, São Carlos, SP 13563-120, Brasil São Carlos, Brazil
Gilles Courtemanche
4Bioaster, 28, rue du Docteur Roux, 75015 Paris, France
Marcos S. Buckeridge
5Department of Botany, Institute of Biological Sciences, University of Sao Paulo, Rua do Matão, 277, Sao Paulo-SP 05508-900, Brazil
Édison L. Durigon
1Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo-SP 05508-900, Brazil
Carolina B. Moraes
6Department of Pharmaceutical Sciences, Federal University of Sao Paulo, Rua São Nicolau, 210, Diadema – SP 09913-030, Brazil
Lucio H. Freitas-Junior
1Department of Microbiology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374, Sao Paulo-SP 05508-900, Brazil

Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Posted July 10, 2020.
Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Douglas Ferreira Sales-Medina, Ludmila Rodrigues Pinto Ferreira, Lavínia M. D. Romera, Karolina Ribeiro Gonçalves, Rafael V. C. Guido, Gilles Courtemanche, Marcos S. Buckeridge, Édison L. Durigon, Carolina B. Moraes, Lucio H. Freitas-Junior
bioRxiv 2020.07.09.196337; doi: https://doi.org/10.1101/2020.07.09.196337
Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict their potential to treat covid-19
Douglas Ferreira Sales-Medina, Ludmila Rodrigues Pinto Ferreira, Lavínia M. D. Romera, Karolina Ribeiro Gonçalves, Rafael V. C. Guido, Gilles Courtemanche, Marcos S. Buckeridge, Édison L. Durigon, Carolina B. Moraes, Lucio H. Freitas-Junior
bioRxiv 2020.07.09.196337; doi: https://doi.org/10.1101/2020.07.09.196337
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