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Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing
View ORCID ProfileMitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler, Logan J. Blaine, Yu Yao, Cheng-Zhong Zhang, Mitchell J. Weiss, David Pellman
doi: https://doi.org/10.1101/2020.07.13.200998
Mitchell L. Leibowitz
1Howard Hughes Medical Institute, Chevy Chase, MD, USA
2Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Stamatis Papathanasiou
2Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Phillip A. Doerfler
4Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN
Logan J. Blaine
2Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Yu Yao
4Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN
Cheng-Zhong Zhang
5Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
6Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
Mitchell J. Weiss
4Department of Hematology, St. Jude Children’s Research Hospital, Memphis, TN
David Pellman
1Howard Hughes Medical Institute, Chevy Chase, MD, USA
2Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
3Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
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Posted July 13, 2020.
Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing
Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler, Logan J. Blaine, Yu Yao, Cheng-Zhong Zhang, Mitchell J. Weiss, David Pellman
bioRxiv 2020.07.13.200998; doi: https://doi.org/10.1101/2020.07.13.200998
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