Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Sleep-learning Impairs Subsequent Wake-learning

View ORCID ProfileSimon Ruch, View ORCID ProfileMarc Alain Züst, Katharina Henke
doi: https://doi.org/10.1101/2020.07.16.206482
Simon Ruch
1Cognitive Neuroscience of Memory and Consciousness, Institute of Psychology, University of Bern, Fabrikstrasse 8, 3012 Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Simon Ruch
  • For correspondence: simon.ruch@psy.unibe.ch
Marc Alain Züst
1Cognitive Neuroscience of Memory and Consciousness, Institute of Psychology, University of Bern, Fabrikstrasse 8, 3012 Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Marc Alain Züst
Katharina Henke
1Cognitive Neuroscience of Memory and Consciousness, Institute of Psychology, University of Bern, Fabrikstrasse 8, 3012 Bern, Switzerland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Humans can unconsciously acquire new information during deep sleep. Although sleep-played information can guide behavior during subsequent wakefulness, sleep-formed memories cannot be remembered consciously after awakening. We explored whether sleep-learning might expedite conscious learning during subsequent wakefulness by providing a first bout of carving a new memory trace, which ensuing wake-learning can build on. We analyzed previously unreported data acquired in a recent study on vocabulary learning during slow-wave sleep (Züst et al., 2019, Curr Biol). Sleep-played vocabulary was successfully retrieved in an implicit memory test administered following awakening. However, sleep-learning diminished instead of increased wake relearning of the same vocabulary. We speculate that vocabulary learning during sleep may have interfered with the synaptic down-scaling of hippocampal and neocortical language-related neurons, which were then too saturated for further potentiation required for the wake-relearning of the same vocabulary.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted July 24, 2020.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Sleep-learning Impairs Subsequent Wake-learning
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Sleep-learning Impairs Subsequent Wake-learning
Simon Ruch, Marc Alain Züst, Katharina Henke
bioRxiv 2020.07.16.206482; doi: https://doi.org/10.1101/2020.07.16.206482
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Sleep-learning Impairs Subsequent Wake-learning
Simon Ruch, Marc Alain Züst, Katharina Henke
bioRxiv 2020.07.16.206482; doi: https://doi.org/10.1101/2020.07.16.206482

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (2646)
  • Biochemistry (5270)
  • Bioengineering (3682)
  • Bioinformatics (15798)
  • Biophysics (7259)
  • Cancer Biology (5629)
  • Cell Biology (8102)
  • Clinical Trials (138)
  • Developmental Biology (4769)
  • Ecology (7522)
  • Epidemiology (2059)
  • Evolutionary Biology (10585)
  • Genetics (7733)
  • Genomics (10137)
  • Immunology (5197)
  • Microbiology (13918)
  • Molecular Biology (5390)
  • Neuroscience (30799)
  • Paleontology (215)
  • Pathology (879)
  • Pharmacology and Toxicology (1525)
  • Physiology (2255)
  • Plant Biology (5025)
  • Scientific Communication and Education (1042)
  • Synthetic Biology (1388)
  • Systems Biology (4149)
  • Zoology (812)