The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner

Junko Ogawa; Wei Zhu; Nina Tonnu; Oded Singer; Tony Hunter; Amy L Ryan (Firth); Gerald M Pao

doi:10.1101/2020.07.21.214932

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The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner

Junko Ogawa, Wei Zhu, Nina Tonnu, Oded Singer, Tony Hunter, Amy L Ryan (Firth), View ORCID ProfileGerald M Pao

doi: https://doi.org/10.1101/2020.07.21.214932

Junko Ogawa

1Salk Institute for Biological Studies. Molecular and Cellular Biology Laboratory 4, 10010 North Torrey Pines Rd. La Jolla CA 92037

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Wei Zhu

2University of California, San Diego. Department of Biology, 9500 Gilman Drive, La Jolla CA 92093

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Nina Tonnu

1Salk Institute for Biological Studies. Molecular and Cellular Biology Laboratory 4, 10010 North Torrey Pines Rd. La Jolla CA 92037

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Oded Singer

3Life Sciences Core Facilities, Weizmann Institute of Science, 7610001 Rehovot, Israel

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Tony Hunter

1Salk Institute for Biological Studies. Molecular and Cellular Biology Laboratory 4, 10010 North Torrey Pines Rd. La Jolla CA 92037

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Amy L Ryan (Firth)

4Hastings Center for Pulmonary Research, Department of Pulmonary, Critical Care and Sleep Medicine, USC Keck School of Medicine, 2011 Zonal Avenue, Los Angeles, CA 90033

5Department of Stem Cell and Regenerative Medicine, University of Southern California, 1405 San Pablo Street, Los Angeles, CA, USA

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Gerald M Pao

1Salk Institute for Biological Studies. Molecular and Cellular Biology Laboratory 4, 10010 North Torrey Pines Rd. La Jolla CA 92037

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ORCID record for Gerald M Pao
For correspondence: pao@salk.edu

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Posted July 22, 2020.

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The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner

Junko Ogawa, Wei Zhu, Nina Tonnu, Oded Singer, Tony Hunter, Amy L Ryan (Firth), Gerald M Pao

bioRxiv 2020.07.21.214932; doi: https://doi.org/10.1101/2020.07.21.214932

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The D614G mutation in the SARS-CoV2 Spike protein increases infectivity in an ACE2 receptor dependent manner

Junko Ogawa, Wei Zhu, Nina Tonnu, Oded Singer, Tony Hunter, Amy L Ryan (Firth), Gerald M Pao

bioRxiv 2020.07.21.214932; doi: https://doi.org/10.1101/2020.07.21.214932

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