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SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation and are not inhibited by Bromhexine

Bojan F. Hörnich, Anna K. Großkopf, Sarah Schlagowski, Matthias Tenbusch, Frank Neipel, Alexander S. Hahn
doi: https://doi.org/10.1101/2020.07.25.221135
Bojan F. Hörnich
1Nachwuchsgruppe Herpesviren, Abteilung Infektionsbiologie, Deutsches Primatenzentrum – Leibniz-Institut für Primatenforschung, Göttingen, Germany
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Anna K. Großkopf
1Nachwuchsgruppe Herpesviren, Abteilung Infektionsbiologie, Deutsches Primatenzentrum – Leibniz-Institut für Primatenforschung, Göttingen, Germany
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Sarah Schlagowski
1Nachwuchsgruppe Herpesviren, Abteilung Infektionsbiologie, Deutsches Primatenzentrum – Leibniz-Institut für Primatenforschung, Göttingen, Germany
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Matthias Tenbusch
2Virologisches Institut, Universitätsklinikum Erlangen, Erlangen, Germany
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Frank Neipel
2Virologisches Institut, Universitätsklinikum Erlangen, Erlangen, Germany
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Alexander S. Hahn
1Nachwuchsgruppe Herpesviren, Abteilung Infektionsbiologie, Deutsches Primatenzentrum – Leibniz-Institut für Primatenforschung, Göttingen, Germany
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  • For correspondence: ahahn@dpz.eu
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Article Information

doi 
https://doi.org/10.1101/2020.07.25.221135
History 
  • July 30, 2020.

Article Versions

  • Version 1 (July 25, 2020 - 21:48).
  • You are currently viewing Version 2 of this article (July 30, 2020 - 17:03).
  • Version 3 (January 5, 2021 - 16:48).
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Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Bojan F. Hörnich1,
  2. Anna K. Großkopf1,
  3. Sarah Schlagowski1,
  4. Matthias Tenbusch2,
  5. Frank Neipel2 and
  6. Alexander S. Hahn1,*
  1. 1Nachwuchsgruppe Herpesviren, Abteilung Infektionsbiologie, Deutsches Primatenzentrum – Leibniz-Institut für Primatenforschung, Göttingen, Germany
  2. 2Virologisches Institut, Universitätsklinikum Erlangen, Erlangen, Germany
  1. ↵*Correspondence to: ahahn{at}dpz.eu
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Posted July 30, 2020.
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SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation and are not inhibited by Bromhexine
Bojan F. Hörnich, Anna K. Großkopf, Sarah Schlagowski, Matthias Tenbusch, Frank Neipel, Alexander S. Hahn
bioRxiv 2020.07.25.221135; doi: https://doi.org/10.1101/2020.07.25.221135
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SARS-CoV-2 and SARS-CoV spike-mediated cell-cell fusion differ in the requirements for receptor expression and proteolytic activation and are not inhibited by Bromhexine
Bojan F. Hörnich, Anna K. Großkopf, Sarah Schlagowski, Matthias Tenbusch, Frank Neipel, Alexander S. Hahn
bioRxiv 2020.07.25.221135; doi: https://doi.org/10.1101/2020.07.25.221135

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