Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior

Matthew G. Perich; Sara Conti; Marion Badi; Andrew Bogaard; Beatrice Barra; Sophie Wurth; Jocelyne Bloch; Gregoire Courtine; Silvestro Micera; Marco Capogrosso; Tomislav Milekovic

doi:10.1101/2020.07.30.228767

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Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior

View ORCID ProfileMatthew G. Perich, Sara Conti, Marion Badi, View ORCID ProfileAndrew Bogaard, Beatrice Barra, View ORCID ProfileSophie Wurth, View ORCID ProfileJocelyne Bloch, View ORCID ProfileGregoire Courtine, View ORCID ProfileSilvestro Micera, View ORCID ProfileMarco Capogrosso, View ORCID ProfileTomislav Milekovic

doi: https://doi.org/10.1101/2020.07.30.228767

Matthew G. Perich

1Department of Fundamental Neuroscience, University of Geneva, Geneva, Switzerland

2Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA

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For correspondence: mperich@gmail.com

Sara Conti

3Department of Medicine, University of Fribourg, Fribourg, Switzerland

4The BioRobotics Institute and Department of Excellent in Robotics and AI, Scuola Superiore Sant’Anna, Pisa, Italy

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Marion Badi

5Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Andrew Bogaard

5Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Beatrice Barra

3Department of Medicine, University of Fribourg, Fribourg, Switzerland

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Sophie Wurth

5Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Jocelyne Bloch

6Centre hospitalier universitaire Vaudois (CHUV), Lausanne, Switzerland

7Defitech Center for Interventional Neurotherapies (NeuroRestore), Lausanne, Switzerland

8Center for Neuroprosthetics and the Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Gregoire Courtine

6Centre hospitalier universitaire Vaudois (CHUV), Lausanne, Switzerland

7Defitech Center for Interventional Neurotherapies (NeuroRestore), Lausanne, Switzerland

8Center for Neuroprosthetics and the Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Silvestro Micera

4The BioRobotics Institute and Department of Excellent in Robotics and AI, Scuola Superiore Sant’Anna, Pisa, Italy

5Bertarelli Foundation Chair in Translational Neuroengineering, Center for Neuroprosthetics and Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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Marco Capogrosso

3Department of Medicine, University of Fribourg, Fribourg, Switzerland

9Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA

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Tomislav Milekovic

1Department of Fundamental Neuroscience, University of Geneva, Geneva, Switzerland

6Centre hospitalier universitaire Vaudois (CHUV), Lausanne, Switzerland

7Defitech Center for Interventional Neurotherapies (NeuroRestore), Lausanne, Switzerland

8Center for Neuroprosthetics and the Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

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ORCID record for Tomislav Milekovic

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Posted August 03, 2020.

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Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior

Matthew G. Perich, Sara Conti, Marion Badi, Andrew Bogaard, Beatrice Barra, Sophie Wurth, Jocelyne Bloch, Gregoire Courtine, Silvestro Micera, Marco Capogrosso, Tomislav Milekovic

bioRxiv 2020.07.30.228767; doi: https://doi.org/10.1101/2020.07.30.228767

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Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior

Matthew G. Perich, Sara Conti, Marion Badi, Andrew Bogaard, Beatrice Barra, Sophie Wurth, Jocelyne Bloch, Gregoire Courtine, Silvestro Micera, Marco Capogrosso, Tomislav Milekovic

bioRxiv 2020.07.30.228767; doi: https://doi.org/10.1101/2020.07.30.228767

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