Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

Louis-Jan Pilaz; Kaumudi Joshi; Jing Liu; Yuji Tsunekawa; Fernando C. Alsina; Sahil Sethi; Ikuo K. Suzuki; Pierre Vanderhaeghen; Franck Polleux; Debra L. Silver

doi:10.1101/2020.07.30.229724

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Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

Louis-Jan Pilaz, Kaumudi Joshi, Jing Liu, Yuji Tsunekawa, Fernando C. Alsina, Sahil Sethi, Ikuo K. Suzuki, Pierre Vanderhaeghen, View ORCID ProfileFranck Polleux, View ORCID ProfileDebra L. Silver

doi: https://doi.org/10.1101/2020.07.30.229724

Louis-Jan Pilaz

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 USA

2Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD 57104 USA

3Department of Pediatrics, Sanford School of Medicine, University of South Dakota, Sioux Falls, SD 57105 USA

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Kaumudi Joshi

4Department of Neuroscience, Columbia University Medical Center, New York, NY, USA

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Jing Liu

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 USA

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Yuji Tsunekawa

5Laboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan

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Fernando C. Alsina

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 USA

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Sahil Sethi

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 USA

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Ikuo K. Suzuki

6Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan

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Pierre Vanderhaeghen

7VIB-KU Leuven Center for Brain & Disease Research, 3000 Leuven, Belgium

8KU Leuven, Department of Neurosciences & Leuven Brain Institute, 3000 Leuven, Belgium

9Université Libre de Bruxelles (U.L.B.), Institut de Recherches en Biologie Humaine et Moléculaire (IRIBHM), and ULB Neuroscience Institute (UNI), 1070 Brussels, Belgium

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Franck Polleux

4Department of Neuroscience, Columbia University Medical Center, New York, NY, USA

10Mortimer B. Zuckerman Mind Brain Behavior Institute, New York, NY USA

11Kavli Institute for Brain Sciences, Columbia University Medical Center, New York, NY USA

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ORCID record for Franck Polleux

Debra L. Silver

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710 USA

12Departments of Cell Biology and Neurobiology, Duke University Medical Center, Durham, NC 27710 USA

13Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC 27710 USA

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ORCID record for Debra L. Silver
For correspondence: debra.silver@duke.edu

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Posted July 31, 2020.

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Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

Louis-Jan Pilaz, Kaumudi Joshi, Jing Liu, Yuji Tsunekawa, Fernando C. Alsina, Sahil Sethi, Ikuo K. Suzuki, Pierre Vanderhaeghen, Franck Polleux, Debra L. Silver

bioRxiv 2020.07.30.229724; doi: https://doi.org/10.1101/2020.07.30.229724

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Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

Louis-Jan Pilaz, Kaumudi Joshi, Jing Liu, Yuji Tsunekawa, Fernando C. Alsina, Sahil Sethi, Ikuo K. Suzuki, Pierre Vanderhaeghen, Franck Polleux, Debra L. Silver

bioRxiv 2020.07.30.229724; doi: https://doi.org/10.1101/2020.07.30.229724

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