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Elucidating the mechanism of cyclodextrins in the treatment of Niemann-Pick Disease Type C using crosslinked 2-hydroxypropyl-β-cyclodextrin
Dario Carradori, Hsintsung Chen, Beat Werner, Aagam Shah, Chiara Leonardi, Mattia Usuelli, Raffaele Mezzenga, Frances Platt, View ORCID ProfileJean-Christophe Leroux
doi: https://doi.org/10.1101/2020.07.31.230136
Dario Carradori
1Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich, Switzerland
Hsintsung Chen
2Department of Pharmacology, University of Oxford, Oxford, United Kingdom
Beat Werner
3Center for MR-Research, University Children’s Hospital, Zürich, Switzerland
Aagam Shah
4Institute of Neuroinformatics, ETH Zürich and University of Zürich, Zürich, Switzerland
Chiara Leonardi
1Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich, Switzerland
Mattia Usuelli
5Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland
Raffaele Mezzenga
5Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland
Frances Platt
2Department of Pharmacology, University of Oxford, Oxford, United Kingdom
Jean-Christophe Leroux
1Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zürich, Zürich, Switzerland
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Posted July 31, 2020.
Elucidating the mechanism of cyclodextrins in the treatment of Niemann-Pick Disease Type C using crosslinked 2-hydroxypropyl-β-cyclodextrin
Dario Carradori, Hsintsung Chen, Beat Werner, Aagam Shah, Chiara Leonardi, Mattia Usuelli, Raffaele Mezzenga, Frances Platt, Jean-Christophe Leroux
bioRxiv 2020.07.31.230136; doi: https://doi.org/10.1101/2020.07.31.230136
Elucidating the mechanism of cyclodextrins in the treatment of Niemann-Pick Disease Type C using crosslinked 2-hydroxypropyl-β-cyclodextrin
Dario Carradori, Hsintsung Chen, Beat Werner, Aagam Shah, Chiara Leonardi, Mattia Usuelli, Raffaele Mezzenga, Frances Platt, Jean-Christophe Leroux
bioRxiv 2020.07.31.230136; doi: https://doi.org/10.1101/2020.07.31.230136
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