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A novel prokaryotic CRISPR-Cas12a based tool for programmable transcriptional activation and repression
Christoph Schilling, Mattheos Koffas, Volker Sieber, Jochen Schmid
doi: https://doi.org/10.1101/2020.08.05.232744
Christoph Schilling
1Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany
Mattheos Koffas
2Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York 12180, United States
3Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, United States
Volker Sieber
1Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany
4Fraunhofer IGB, Straubing Branch BioCat, Schulgasse 23, 94315, Straubing, Germany
5TUM Catalysis Research Center, Ernst-Otto-Fischer-Straße1, 85748, Garching, Germany
6The University of Queensland, School of Chemistry and Molecular Biosciences, 68 Copper Road, St. Lucia, 4072, Australia
Jochen Schmid
1Chair of Chemistry of Biogenic Resources, Technical University of Munich, Campus for Biotechnology and Sustainability, Schulgasse 16, 94315, Straubing, Germany
7Institute for Molecular Microbiology and Biotechnology, Westfälische Wilhelms-Universität Münster, Corrensstrasse 3, 48149 Münster, Germany
Posted August 05, 2020.
A novel prokaryotic CRISPR-Cas12a based tool for programmable transcriptional activation and repression
Christoph Schilling, Mattheos Koffas, Volker Sieber, Jochen Schmid
bioRxiv 2020.08.05.232744; doi: https://doi.org/10.1101/2020.08.05.232744
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